Glaucoma, Open-Angle
Conditions
Brief summary
Investigate changes in optical coherence tomography angiography of the optic nerve and macula following topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution.
Interventions
Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)
Sponsors
University of the Incarnate Word
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Normal ocular health
Exclusion criteria
* Females who are or may be pregnant or who are nursing * Uncontrolled hypertension * Allergy to netarsudil or latanoprost
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Peripapillary capillary perfusion density | 90 minutes | Mean change in peripapillary capillary perfusion as assessed using optical coherence tomography angiography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Macular capillary perfusion density | 90 minutes | Mean change in macular capillary perfusion as assessed using optical coherence tomography angiography |
Countries
United States
Contacts
Primary ContactMary Jo Bilicek
Outcome results
None listed