Perfusion, Perioperative/Postoperative Complications
Conditions
Keywords
Common carotid artery, Trendelenburg, Pneumoperitoneum, Blood flow
Brief summary
The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.
Detailed description
The study will include 20 patients undergoing gynecological surgery. The common carotid artery blood flow will be measured using Doppler US during the following conditions; supine position before induction of anesthesia, supine position immediately after induction of anesthesia, supine position with penumoperitoneum, head-down position with or without pneumoperitoneum.
Interventions
None listed
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* ASA class I,II * patients undergoing gynecology surgery under trendelenburg position * Age ranges from 20 to 70
Exclusion criteria
* BMI \> 32 * Pregnancy * Patients who did not agree to study * Patients with allergies to the drugs used in this study * Patients with anatomical variations or lesions in cervical or cranial vascular portion * Patients with arrhythmia that may alter patient's cardiac output(e.g. artrial fibrillation)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of the common carotid artery blood flow velocity | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Common carotid artery blood flow velocity is measured using Doppler US |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of the common carotid artery beat volume | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Common carotid artery beat volume was calculated from median common carotid artery beat velocity and vessel diameter |
| Change of the common carotid artery diameter | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Common carotid artery diameter is obtained using US |
| Change of mean arterial blood pressure | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Mean arterial pressure is obtained concurrently with common carotid artery blood flow velocity measurements |
| Change of cardiac output | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Cardiac output was obtained using FloTrac(EdwardLifescience, USA) |
| Change of peak inspiration airway pressure | 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position | Peak inspiratory airway pressure is obtained using the ventilator system |
Countries
South Korea
Outcome results
None listed