Planned Vaginal Delivery vs Planned Cesarean Delivery in Preterm Twins

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04232436

Enrollment

204

Registered

2020-01-18

Start date

2019-07-01

Completion date

2020-03-01

Last updated

2020-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Twin Pregnancy

Keywords

Mode of delivery, Prematurity, Survival at discharge, Survival without severe morbidity

Brief summary

The incidence of twin pregnancies has increased and currently accounts for 1.8% of all deliveries. 47.5% of twins are born prematurely (vs. 6% for singletons) of which 9.9% before 32SA. Caesarean section rates are also higher than for singletons (53.7% vs 19.2%) and 31.8% of caesarean sections are performed before delivery. The optimal mode of delivery for preterm twins remains controversial. The latest recommendations for clinical practice emphasize that it is not appropriate to recommend one mode of delivery rather than another in the case of twin pregnancies at any term. In view of all these elements, we wished to carry out a retrospective study at the Montpellier University Hospital in order to compare the neonatal outcome of preterms twins according to their mode of delivery : planned vaginal delivery versus planned cesarean delivery.

Interventions

OTHERSurvival at discharge

Survival at discharge

OTHERSurvival without severe morbidity

Survival without severe morbidity (IVH, severe BPD, NEC, ROP)

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* twins born at Montpellier University Hospital * between 24SA and 32SA+6 * January 2010 to July 2019 * The mothers must have gone into labour spontaneously or after preterm rupture of membranes * first twin in cephalic presentation

Exclusion criteria

* twin to twin transfusion syndrome * monoamniotic pregnancies * cause of delivery other than preterm labor or preterm rupture of membranes * lethal malformation * first twin in breech or transverse presentation

Design outcomes

Primary

Measure	Time frame	Description
survival at discharge and survival	during neonatal hospitalization	survival at discharge and survival without severe morbidity

Secondary

Measure	Time frame	Description
survival at 2 years of corrected	during the first two years corrected age	survival at 2 years of corrected
age without neurosensory impairment	during the first two years corrected age	age without neurosensory impairment

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026