Post-extraction Bone Regeneration
Conditions
Keywords
tooth extraction, alveolar bone, bone regeneration, laser
Brief summary
Alveolar bone regeneration after laser-assisted extraction will be compared with bone regeneration after standard extraction procedure.
Interventions
DEVICEEr:YAG and Nd:YAG lasers
Extraction followed by Er:YAG laser degranulation, Nd:YAG laser disinfection, Er:YAG deepithelialization, Nd:YAG blood clot stabilization and photobiomodulation. The photobiomodulation step repeated on day 3, 5, and 7.
PROCEDUREStandard extraction
Standard extraction procedure
Sponsors
Krizaj d.o.o.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
CBCT will be used to assess bone density and the assessors will be unaware of the patient allocation.
Intervention model description
Patients will be randomly assigned to either laser or control group.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patient requires at least one simple extraction * Voluntary informed consent to participate in the study
Exclusion criteria
* Pregnancy * Use of photosensitizing medication * Refuse participation * Require complicated extraction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in bone density from immediate post-extraction | 3 months | Cone Beam Computed Tomography (CBCT) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bone density | 3 months | Cone Beam Computed Tomography (CBCT) |
| Bone thickness | 3 months | Cone Beam Computed Tomography (CBCT) |
| Treatment pain | day 1 | On a pain scale from 0 (no pain) to 10 (intolerable pain) |
Countries
Slovenia
Outcome results
None listed