Effect of Feet and Calf Heating on Glucose Tolerance

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04232098

Enrollment

Registered

2020-01-18

Start date

2019-02-01

Completion date

2021-02-01

Last updated

2024-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Rate Variability, Postprandial Hyperglycemia

Brief summary

Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).

Interventions

OTHERHeat to ankle

Heat administered via hot water to ankle level

OTHERHeat to calf

Heat administered via hot water to calf level

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Anyone within specified age range

Exclusion criteria

* Anyone outside specified age range

Design outcomes

Primary

Measure	Time frame
Blood Glucose	30 minute

Secondary

Measure	Time frame
Blood Pressure	30 min
Tympanic Temperature	30 min

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026