Dental Caries in Children
Conditions
Keywords
Dental caries, IGF-1, IGFBP-3, anthropometry, sleeping
Brief summary
Untreated dental caries are very common in preschool children. Pain and inflammation due to dental caries have been reported to affect eating and sleeping disorders, affecting growth and development. The aim of this study was to compare the changes in serum IGF-1 and IGFBP-3 levels, height and weight gain before and after treatment in patients with dental caries-related inflammation and pain in preschool children and to compare these children with children without dental caries. Thirty children aged between 3-6 years with dental caries with pulp were identified using ICDAS II and dmft index as the study group.30 children dental caries including pulp, will be included using the same indices as the control group. In the study group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined before and at the 6th month after treatment. In the control group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined at the 6th month following the first dental examination. IGF-1, IGFBP-3 and anthropometric measurements will be compared between first dental examination and 6th month values in the study and control groups, and between first dental examination and 6th month time points between the groups.
Detailed description
In addition to growth parameters, the Children's Sleeping Habits Questionnaire and the Early Childhood Oral Health Impact Scale will be compared before the 6th month of dental treatment and compared
Interventions
OTHERdental caries, growth parametres
The comparison of growth parameters before and after 6 months of treatment of dental caries will be compared. Children's Sleep Habits Questionnaire and Early Childhood Oral Health Impact Scale will be compared before and at the 6th month of dental treatment.
Sponsors
Bezmialem Vakif University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
3 Years to 6 Years
Healthy volunteers
Yes
Inclusion criteria
For study group 1. (3-6 years) preschool children 2. Children whose dental treatments are indicated under general anesthesia 3. Children with primary dentition 4. Children with early childhood caries (dmft index d≥ 3) 5. Children with symptoms of pulpitis or periapical infection in at least one tooth 6. Children with dental problems at least in the last 6 months 7. Volunteering to participate in the study. For the control group, 1- (3-6 years) preschool children 2-Children with primary dentition 3- Children without pulpitis symptoms or periapical infection during dental examination 4-Volunteering to participate in the study.
Exclusion criteria
1. Children who do not show adequate compliance during blood sampling 2. Consent form is not signed 3. Children with chronic and systemic diseases that may affect growth and development 4. Children using anti-inflammatory 5. Patients with physical and mental disabilities 6. Patients using corticosteroids in the last 6 months 7. If a child is diagnosed with any of the these diseases during the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Growth parameters | before dental treatment | In the study group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined before and at the 6th month after treatment. In the control group, serum IGF-1 and IGFBP-3 levels and anthropometric measurements will be determined at the 6th month following the first dental examination. IGF-1, IGFBP-3 and anthropometric measurements will be compared between first dental examination and 6th month values in the study and control groups, and between first dental examination and 6th month time points between the groups. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Children's Sleep Habits Questionnaire | before dental treatment | In the study group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment.In the control group Children's Sleep Habits Questionnaire will be compared before, after the a week and 6th month of dental treatment |
| Early Childhood Oral Health Impact Scale | before dental treatment | n the study Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment.In the control group Early Childhood Oral Health Impact Scale will be compared before, after the a week and 6th month of dental treatment |
Countries
Turkey (Türkiye)
Outcome results
None listed