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VR System for Cross-modal Rehabilitation of Hemianopia

Virtual Reality System for Cross-modal Rehabilitation of Hemianopia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04230486
Enrollment
6
Registered
2020-01-18
Start date
2020-06-29
Completion date
2021-07-30
Last updated
2022-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemianopia, Homonymous, Hemianopsia, Homonymous

Keywords

Hemianopia, Virtual Reality, Rehabilitation, Hemianopsia

Brief summary

The purpose of this research study is to investigate the effectiveness of a new rehabilitation for visual hemianopia. The study team believes a cross-modal rehabilitation technique delivered by a virtual reality system can help restore the visual field for subjects with homonymous hemianopia.

Detailed description

The study tests a novel rehabilitation system, translated from promising cross-modal rehabilitation animal research, that is the first treatment capable of restoring the visual field for hemianopia patients. This noninvasive technique uses a virtual reality device to deliver visual and auditory stimulus. The goals of this study are to obtain proof of concept and procure rehabilitation data to support the development of this novel rehabilitation treatment.

Interventions

DEVICECross-model Visual Auditory Rehabilitation

Subjects will put on a virtual reality rehabilitation system which will present sights and sounds.

Sponsors

Wake Forest University Health Sciences
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

All study participants will be given the same treatment.

Eligibility

Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No

Inclusion criteria

* Adult volunteers diagnosed with homonymous visual hemianopia / hemianopsia (ages 18-99)

Exclusion criteria

* Volunteers who are unable to complete the study tasks or understand instructions * Subjects that are not able to provide written consent or verbal assent * Subjects who are not available to complete all rehabilitation sessions

Design outcomes

Primary

MeasureTime frameDescription
Humphrey Visual Field PerimetryBaselineThe area of the subject's visual field measured by 30-2 Humphrey visual field (HVF) perimetry. Both left and right sides will be tested. The deficit side includes is the hemianopic side. The intact side is the non-hemianopic side. During the HVF test, light is projected into a white bowl with a standardized background light intensity to form a circular stimulus, around 30 cm away from the patient's eye. The overall field mapping technique used is a form of static perimetry, where a stimulus appears in various areas of the field of vision. The patient indicates when they can see the stimulus and the perimetrist then records the point where the stimulus was seen. These data points are used to determine the patient's visual field.
Virtual Reality (VR) Visual Field Test--Mean Percent CorrectDay 1Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.
Virtual Reality Visual Field Test--Mean Percent CorrectDay 2Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.
Peripheral Visual Field Frame TestBaselineThe number of points subjects can detect in each location of the visual field along the horizontal meridian. Percent of correct trials in each location tested in the deficit and intact side. Locations at 15°, 30°, 45°, 60°, and 75° on the horizontal meridian on the left and right side were tested.

Secondary

MeasureTime frameDescription
VA LV VFQ-48--Reading Domain ScoreBaseline, 2 monthsThe VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The reading domain score is calculated by calculating the average score of reading items. Scores range from 0 to 3.5 logits, with higher scores denoting better ability to perform activities. The Reading Domain Score is the average functional reserve of the items measuring the reading functional domain, excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons).
Veterans Affairs Low Vision Visual Function Questionnaire-48 (VA LV VFQ-48)--Item ScoreBaseline, 2 monthsThe VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 (most difficult) and \>=-2.22 (least difficult). Scores out of this range indicate something other than visual impairment is governing the patient's responses. The Item Score is the average functional reserve of all the items in the questionnaire excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons). Functional reserve is the difference between a patient's visual ability and the visual ability needed to perform an activity.
VA LV VFQ-48--Item Score3 monthsThe VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 (most difficult) and \>=-2.22 (least difficult). Scores out of this range indicate something other than visual impairment is governing the patient's responses. The Item Score is the average functional reserve of all the items in the questionnaire excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons). Functional reserve is the difference between a patient's visual ability and the visual ability needed to perform an activity.
VA LV VFQ-48--Composite ScoreBaseline, 2 monthsThe VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 and \>=-2.22. Scores out of this range indicate something other than visual impairment is governing the patient's responses. The reading domain score is calculated by calculating the average score of reading items. The composite score approximates a person's visual ability. The score is calculated using Massof's algorithm using the inverse hyperbolic tangent equation. For the composite score, a lower score is better.
National Eye Institute Visual Function Questionnaire (NEI-VFQ-25)--Composite ScoreBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. This score is calculated from the average of all subscale scores in the NEI VFQ-25 excluding the general health score. The score ranges from 0 to 100. A higher score denotes better vision-related quality of life.
NEI-VFQ-25--Composite Score6 monthThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. This score is calculated from the average of all subscale scores in the NEI VFQ-25 excluding the general health score. The score ranges from 0 to 100. A higher score denotes better vision-related quality of life.
NEI-VFQ-25--General Health Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Health Score is a subscale that measures the participant's self-report of their overall health. The score ranges from 0 to 100. A higher score denotes better perception of overall health.
NEI-VFQ-25--General Vision Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Vision Score measures the participant's reported quality of vision. The score ranges from 0 to 100. A higher score denotes a better perception of vision
NEI-VFQ-25--Ocular Pain Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Ocular Pain Score Subscale measures reported pain or discomfort in and around the eyes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to ocular pain.
NEI-VFQ-25--Near Activities Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Near Activities Score Subscale measures difficulty with performing near activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to near activities.
NEI-VFQ-25--Distance Activities Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Distance Activities Score Subscale measures difficulty with performing distance activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to distance activities.
NEI-VFQ-25--Social Functioning Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Social Functioning Score Subscale measures how vision difficulties affect social functioning. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to social functioning.
NEI-VFQ-25--Mental Health Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Mental Health Score Subscale measures how much patients feel vision affects their mental health. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to mental health.
NEI-VFQ-25--Role Difficulties Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Role Difficulties Score Subscale measures how limited by their vision patients feel they are. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to role difficulties.
NEI-VFQ-25--Dependency Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Dependency Score Subscale measures how much patients are dependent on other people due to their vision. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to dependency.
NEI-VFQ-25--Driving Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Driving Score Subscale measures patients' reported difficulty with driving. The score ranges from 0 to 100. Patients who do not drive are not given a driving score. A higher score denotes better vision-specific quality of life related to driving.
NEI-VFQ-25--Color Vision Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Color Vision Score Subscale measures how much difficulty patients have with using color vision to complete daily activities such as picking out clothes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to color vision.
NEI-VFQ-25--Peripheral Vision Score SubscaleBaseline, 2 months, 3 monthsThe NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Peripheral Vision Score Subscale measures how much difficulty patients have with their peripheral vision to complete daily activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to peripheral vision.

Other

MeasureTime frameDescription
Color Vision TestFirst visit after the completion of rehabilitation (1 or 2 months)Change in the percentage of correctly identified trials for each color.
Shape Recognition TestFirst visit after the completion of rehabilitation (1 or 2 months)Change in the percentage of correctly identified trials.
Grating Acuity TestFirst visit after the completion of rehabilitation (1 or 2 months)Change in the percentage of correctly identified trials.

Countries

United States

Participant flow

Recruitment details

Six subjects signed consent. One screen failed.

Participants by arm

ArmCount
Experimental Group Virtual Reality (VR) Treatment
Visual Auditory Virtual Reality rehabilitation for visual hemianopia Cross-model Visual Auditory Rehabilitation: Subjects will put on a virtual reality rehabilitation system which will present sights and sounds.
5
Total5

Withdrawals & dropouts

PeriodReasonFG000
Overall StudyScreen Failure1

Baseline characteristics

CharacteristicExperimental Group Virtual Reality (VR) Treatment
Age, Continuous62.6 years
STANDARD_DEVIATION 13.667
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
Race (NIH/OMB)
Asian
0 Participants
Race (NIH/OMB)
Black or African American
0 Participants
Race (NIH/OMB)
More than one race
0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
Race (NIH/OMB)
White
5 Participants
Region of Enrollment
United States
5 participants
Sex: Female, Male
Female
4 Participants
Sex: Female, Male
Male
1 Participants

Adverse events

Event typeEG000
affected / at risk
deaths
Total, all-cause mortality
0 / 6
other
Total, other adverse events
0 / 6
serious
Total, serious adverse events
0 / 6

Outcome results

Primary

Humphrey Visual Field Perimetry

The area of the subject's visual field measured by 30-2 Humphrey visual field (HVF) perimetry. Both left and right sides will be tested. The deficit side includes is the hemianopic side. The intact side is the non-hemianopic side. During the HVF test, light is projected into a white bowl with a standardized background light intensity to form a circular stimulus, around 30 cm away from the patient's eye. The overall field mapping technique used is a form of static perimetry, where a stimulus appears in various areas of the field of vision. The patient indicates when they can see the stimulus and the perimetrist then records the point where the stimulus was seen. These data points are used to determine the patient's visual field.

Time frame: Baseline

Population: Analysis only includes subjects who completed study.

ArmMeasureValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeHumphrey Visual Field Perimetry108 visual angle degrees^2Standard Deviation 198.49
Virtual Reality (VR) Treatment-IntactHumphrey Visual Field Perimetry1272 visual angle degrees^2Standard Deviation 117.58
Primary

Humphrey Visual Field Perimetry

The area of the subject's visual field measured by 30-2 Humphrey visual field (HVF) perimetry. Both left and right sides will be tested. The deficit side includes is the hemianopic side. The intact side is the non-hemianopic side. During the HVF test, light is projected into a white bowl with a standardized background light intensity to form a circular stimulus, around 30 cm away from the patient's eye. The overall field mapping technique used is a form of static perimetry, where a stimulus appears in various areas of the field of vision. The patient indicates when they can see the stimulus and the perimetrist then records the point where the stimulus was seen. These data points are used to determine the patient's visual field.

Time frame: up to 2 Months

Population: Analysis only includes subjects who completed study.

ArmMeasureValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeHumphrey Visual Field Perimetry594 visual angle degrees^2Standard Deviation 542.99
Virtual Reality (VR) Treatment-IntactHumphrey Visual Field Perimetry1356 visual angle degrees^2Standard Deviation 18.59
Primary

Peripheral Visual Field Frame Test

The number of points subjects can detect in each location of the visual field along the horizontal meridian. Percent of correct trials in each location tested in the deficit and intact side. Locations at 15°, 30°, 45°, 60°, and 75° on the horizontal meridian on the left and right side were tested.

Time frame: 6 Months

Population: Due to study timeline constraints, only one subject completed the 6 month follow-up test.

ArmMeasureGroupValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test15 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test60 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test30 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test75 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test45 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test75 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test45 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test15 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test30 Degrees100 Percent of correct trials
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test60 Degrees100 Percent of correct trials
Primary

Peripheral Visual Field Frame Test

The number of points subjects can detect in each location of the visual field along the horizontal meridian. Percent of correct trials in each location tested in the deficit and intact side. Locations at 15°, 30°, 45°, 60°, and 75° on the horizontal meridian on the left and right side were tested.

Time frame: Baseline

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test15 Degrees20 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test60 Degrees20 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test45 Degrees20 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test75 Degrees0 Percent of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test30 Degrees20 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test75 Degrees76 Percent of correct trialsStandard Deviation 43.359
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test15 Degrees80 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test30 Degrees80 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test45 Degrees80 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test60 Degrees72 Percent of correct trialsStandard Deviation 43.8178
Primary

Peripheral Visual Field Frame Test

The number of points subjects can detect in each location of the visual field along the horizontal meridian. Percent of correct trials in each location tested in the deficit and intact side. Locations at 15°, 30°, 45°, 60°, and 75° on the horizontal meridian on the left and right side were tested.

Time frame: up to 2 Months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test60 Degrees80 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test45 Degrees92 Percent of correct trialsStandard Deviation 17.8885
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test30 Degrees96 Percent of correct trialsStandard Deviation 8.9443
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test75 Degrees60 Percent of correct trialsStandard Deviation 54.7723
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test15 Degrees100 Percent of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test75 Degrees92 Percent of correct trialsStandard Deviation 17.8885
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test15 Degrees80 Percent of correct trialsStandard Deviation 44.7214
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test60 Degrees100 Percent of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test30 Degrees96 Percent of correct trialsStandard Deviation 8.9443
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test45 Degrees100 Percent of correct trialsStandard Deviation 0
Primary

Peripheral Visual Field Frame Test

The number of points subjects can detect in each location of the visual field along the horizontal meridian. Percent of correct trials in each location tested in the deficit and intact side. Locations at 15°, 30°, 45°, 60°, and 75° on the horizontal meridian on the left and right side were tested.

Time frame: 3 Months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test30 Degrees90 Percent of correct trialsStandard Deviation 20
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test60 Degrees75 Percent of correct trialsStandard Deviation 50
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test45 Degrees80 Percent of correct trialsStandard Deviation 40
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test75 Degrees65 Percent of correct trialsStandard Deviation 47.2582
Virtual Reality (VR) Treatment--Deficit EyePeripheral Visual Field Frame Test15 Degrees95 Percent of correct trialsStandard Deviation 10
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test75 Degrees100 Percent of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test15 Degrees90 Percent of correct trialsStandard Deviation 20
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test30 Degrees90 Percent of correct trialsStandard Deviation 20
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test45 Degrees100 Percent of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactPeripheral Visual Field Frame Test60 Degrees100 Percent of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 4

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 6

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 7

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees58.333 percentage of correct trialsStandard Deviation 35.355
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 8

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 8, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 9

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 10

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 11

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 11, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 12

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.33 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees91.667 percentage of correct trialsStandard Deviation 11.785
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 13

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees41.667 percentage of correct trialsStandard Deviation 58.926
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 14

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees58.333 percentage of correct trialsStandard Deviation 58.926
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 15

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees91.667 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 16

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 17

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 18

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 19

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees91.667 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 20

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 21

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 21, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 22

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 47.14
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees41.667 percentage of correct trialsStandard Deviation 58.926
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees91.667 percentage of correct trialsStandard Deviation 11.785
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 23

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 23, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 24

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 24, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 25

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees58.333 percentage of correct trialsStandard Deviation 58.926
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees66.667 percentage of correct trialsStandard Deviation 47.14
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 26

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 27

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 27, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 28

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19. Data was not collected for 3 subjects due to logistical issues during COVID-19. One subject did not complete the test day 28, so no data was collected for any subjects for this day.

ArmMeasureGroupValue
UnknownVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees
UnknownVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 29

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees66.667 percentage of correct trialsStandard Deviation 47.14
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees50 percentage of correct trialsStandard Deviation 70.711
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 5

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 2

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees16.667 percentage of correct trialsStandard Deviation 23.57
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 3

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees8.333 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct15 Degrees100 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment-IntactVirtual Reality Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Primary

Virtual Reality (VR) Visual Field Test--Mean Percent Correct

Percent of correct trials in each location tested. Location at 15 degrees and 30 degrees on the horizontal meridian on both the left and right side were tested. Virtual Reality Visual Field test is a brief 5-minute test using the VR system to track rehabilitation progress. The test consists of 30 trials with visual stimulus presented either 15° or 30° in either the hemianopia field or the intact field at random time intervals.

Time frame: Day 1

Population: Data was not collected for 3 subjects due to logistical issues during COVID-19.

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality (VR) Visual Field Test--Mean Percent Correct15 Degrees0 percentage of correct trialsStandard Deviation 0
Virtual Reality (VR) Treatment--Deficit EyeVirtual Reality (VR) Visual Field Test--Mean Percent Correct30 Degrees8.33 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality (VR) Visual Field Test--Mean Percent Correct15 Degrees91.667 percentage of correct trialsStandard Deviation 11.785
Virtual Reality (VR) Treatment-IntactVirtual Reality (VR) Visual Field Test--Mean Percent Correct30 Degrees100 percentage of correct trialsStandard Deviation 0
Secondary

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25)--Composite Score

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. This score is calculated from the average of all subscale scores in the NEI VFQ-25 excluding the general health score. The score ranges from 0 to 100. A higher score denotes better vision-related quality of life.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNational Eye Institute Visual Function Questionnaire (NEI-VFQ-25)--Composite ScoreBaseline60.793 score on a scaleStandard Deviation 19.498
Virtual Reality (VR) Treatment--Deficit EyeNational Eye Institute Visual Function Questionnaire (NEI-VFQ-25)--Composite Score2 months68.621 score on a scaleStandard Deviation 21.932
Virtual Reality (VR) Treatment--Deficit EyeNational Eye Institute Visual Function Questionnaire (NEI-VFQ-25)--Composite Score3 months69.893 score on a scaleStandard Deviation 29.418
Secondary

NEI-VFQ-25--Color Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Color Vision Score Subscale measures how much difficulty patients have with using color vision to complete daily activities such as picking out clothes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to color vision.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Color Vision Score SubscaleBaseline75 score on a scaleStandard Deviation 20.412
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Color Vision Score Subscale2 months87.5 score on a scaleStandard Deviation 14.434
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Color Vision Score Subscale3 months87.5 score on a scaleStandard Deviation 17.678
Secondary

NEI-VFQ-25--Color Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Color Vision Score Subscale measures how much difficulty patients have with using color vision to complete daily activities such as picking out clothes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to color vision.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Color Vision Score Subscale100 score on a scale
Secondary

NEI-VFQ-25--Composite Score

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. This score is calculated from the average of all subscale scores in the NEI VFQ-25 excluding the general health score. The score ranges from 0 to 100. A higher score denotes better vision-related quality of life.

Time frame: 6 month

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Composite Score85.87 score on a scale
Secondary

NEI-VFQ-25--Dependency Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Dependency Score Subscale measures how much patients are dependent on other people due to their vision. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to dependency.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Dependency Score SubscaleBaseline41.667 score on a scaleStandard Deviation 35.355
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Dependency Score Subscale2 months50 score on a scaleStandard Deviation 41.388
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Dependency Score Subscale3 months62.5 score on a scaleStandard Deviation 53.033
Secondary

NEI-VFQ-25--Dependency Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Dependency Score Subscale measures how much patients are dependent on other people due to their vision. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to dependency.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Dependency Score Subscale100 score on a scale
Secondary

NEI-VFQ-25--Distance Activities Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Distance Activities Score Subscale measures difficulty with performing distance activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to distance activities.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Distance Activities Score SubscaleBaseline48.333 score on a scaleStandard Deviation 18.609
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Distance Activities Score Subscale2 months76.25 score on a scaleStandard Deviation 19.167
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Distance Activities Score Subscale3 months77.5 score on a scaleStandard Deviation 20.035
Secondary

NEI-VFQ-25--Distance Activities Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Distance Activities Score Subscale measures difficulty with performing distance activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to distance activities.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Distance Activities Score Subscale75 score on a scale
Secondary

NEI-VFQ-25--Driving Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Driving Score Subscale measures patients' reported difficulty with driving. The score ranges from 0 to 100. Patients who do not drive are not given a driving score. A higher score denotes better vision-specific quality of life related to driving.

Time frame: Baseline, 2 months, 3 months

Population: Driving Score Mean and Standard deviation could not be calculated because only one subject was driving and only for the 3 month follow up.

ArmMeasureGroupValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Driving Score Subscale3 months83.333 score on a scale
UnknownNEI-VFQ-25--Driving Score SubscaleBaseline score on a scale
UnknownNEI-VFQ-25--Driving Score Subscale2 months score on a scale
Secondary

NEI-VFQ-25--Driving Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Driving Score Subscale measures patients' reported difficulty with driving. The score ranges from 0 to 100. Patients who do not drive are not given a driving score. A higher score denotes better vision-specific quality of life related to driving.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Driving Score Subscale58.33 score on a scale
Secondary

NEI-VFQ-25--General Health Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Health Score is a subscale that measures the participant's self-report of their overall health. The score ranges from 0 to 100. A higher score denotes better perception of overall health.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Health Score SubscaleBaseline68.75 score on a scaleStandard Deviation 37.5
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Health Score Subscale2 months68.75 score on a scaleStandard Deviation 31.458
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Health Score Subscale3 months62.5 score on a scaleStandard Deviation 17.678
Secondary

NEI-VFQ-25--General Health Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Health Score is a subscale that measures the participant's self-report of their overall health. The score ranges from 0 to 100. A higher score denotes better perception of overall health.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Health Score Subscale50 score on a scale
Secondary

NEI-VFQ-25--General Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Vision Score measures the participant's reported quality of vision. The score ranges from 0 to 100. A higher score denotes a better perception of vision

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Vision Score Subscale80 score on a scale
Secondary

NEI-VFQ-25--General Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The General Vision Score measures the participant's reported quality of vision. The score ranges from 0 to 100. A higher score denotes a better perception of vision

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Vision Score SubscaleBaseline65 score on a scaleStandard Deviation 19.149
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Vision Score Subscale2 months60 score on a scaleStandard Deviation 28.284
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--General Vision Score Subscale3 months70 score on a scaleStandard Deviation 14.142
Secondary

NEI-VFQ-25--Mental Health Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Mental Health Score Subscale measures how much patients feel vision affects their mental health. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to mental health.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Mental Health Score Subscale3 months56.25 score on a scaleStandard Deviation 61.872
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Mental Health Score SubscaleBaseline51.563 score on a scaleStandard Deviation 32.022
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Mental Health Score Subscale2 months48.4375 score on a scaleStandard Deviation 35.858
Secondary

NEI-VFQ-25--Mental Health Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Mental Health Score Subscale measures how much patients feel vision affects their mental health. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to mental health.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Mental Health Score Subscale98.73 score on a scale
Secondary

NEI-VFQ-25--Near Activities Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Near Activities Score Subscale measures difficulty with performing near activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to near activities.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Near Activities Score Subscale75 score on a scale
Secondary

NEI-VFQ-25--Near Activities Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Near Activities Score Subscale measures difficulty with performing near activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to near activities.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Near Activities Score SubscaleBaseline56.25 score on a scaleStandard Deviation 22.948
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Near Activities Score Subscale2 months60.417 score on a scaleStandard Deviation 31.458
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Near Activities Score Subscale3 months75 score on a scaleStandard Deviation 11.785
Secondary

NEI-VFQ-25--Ocular Pain Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Ocular Pain Score Subscale measures reported pain or discomfort in and around the eyes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to ocular pain.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Ocular Pain Score SubscaleBaseline90.625 score on a scaleStandard Deviation 6.25
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Ocular Pain Score Subscale2 months90.625 score on a scaleStandard Deviation 11.968
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Ocular Pain Score Subscale3 months81.25 score on a scaleStandard Deviation 26.517
Secondary

NEI-VFQ-25--Ocular Pain Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Ocular Pain Score Subscale measures reported pain or discomfort in and around the eyes. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to ocular pain.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Ocular Pain Score Subscale100 score on a scale
Secondary

NEI-VFQ-25--Peripheral Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Peripheral Vision Score Subscale measures how much difficulty patients have with their peripheral vision to complete daily activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to peripheral vision.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Peripheral Vision Score SubscaleBaseline50 score on a scaleStandard Deviation 35.3554
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Peripheral Vision Score Subscale2 months81.25 score on a scaleStandard Deviation 37.5
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Peripheral Vision Score Subscale3 months62.5 score on a scaleStandard Deviation 17.678
Secondary

NEI-VFQ-25--Peripheral Vision Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Peripheral Vision Score Subscale measures how much difficulty patients have with their peripheral vision to complete daily activities. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to peripheral vision.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Peripheral Vision Score Subscale75 score on a scale
Secondary

NEI-VFQ-25--Role Difficulties Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Role Difficulties Score Subscale measures how limited by their vision patients feel they are. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to role difficulties.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Role Difficulties Score Subscale100 score on a scale
Secondary

NEI-VFQ-25--Role Difficulties Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Role Difficulties Score Subscale measures how limited by their vision patients feel they are. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life relating to role difficulties.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Role Difficulties Score SubscaleBaseline62.5 score on a scaleStandard Deviation 32.275
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Role Difficulties Score Subscale2 months65.625 score on a scaleStandard Deviation 11.968
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Role Difficulties Score Subscale3 months50 score on a scaleStandard Deviation 70.711
Secondary

NEI-VFQ-25--Social Functioning Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Social Functioning Score Subscale measures how vision difficulties affect social functioning. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to social functioning.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Social Functioning Score Subscale87.5 score on a scale
Secondary

NEI-VFQ-25--Social Functioning Score Subscale

The NEI-VFQ-25 is a 25-item questionnaire regarding the quality of vision, social functioning, visual dependency, near vision, and color vision. The Social Functioning Score Subscale measures how vision difficulties affect social functioning. The score ranges from 0 to 100. A higher score denotes better vision-specific quality of life related to social functioning.

Time frame: Baseline, 2 months, 3 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Social Functioning Score SubscaleBaseline55 score on a scaleStandard Deviation 24.495
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Social Functioning Score Subscale2 months70.625 score on a scaleStandard Deviation 35.259
Virtual Reality (VR) Treatment--Deficit EyeNEI-VFQ-25--Social Functioning Score Subscale3 months87.5 score on a scaleStandard Deviation 17.678
Secondary

VA LV VFQ-48--Composite Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 and \>=-2.22. Scores out of this range indicate something other than visual impairment is governing the patient's responses. The reading domain score is calculated by calculating the average score of reading items. The composite score approximates a person's visual ability. The score is calculated using Massof's algorithm using the inverse hyperbolic tangent equation. For the composite score, a lower score is better.

Time frame: Baseline, 2 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Composite ScoreBaseline-1.607 Score on a ScaleStandard Deviation 1.923
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Composite Score2 Months-2.481 Score on a ScaleStandard Deviation 1.834
Secondary

VA LV VFQ-48--Composite Score

he VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 and \>=-2.22. Scores out of this range indicate something other than visual impairment is governing the patient's responses. The reading domain score is calculated by calculating the average score of reading items. The composite score approximates a person's visual ability. The score is calculated using Massof's algorithm using the inverse hyperbolic tangent equation. For the composite score, a lower score is better.

Time frame: 3 months

Population: Only one subject completed this outcome measure during the 3 month follow-up due to study timeline constraints.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Composite Score-2.415 Score on a Scale
Secondary

VA LV VFQ-48--Composite Score

he VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 and \>=-2.22. Scores out of this range indicate something other than visual impairment is governing the patient's responses. The reading domain score is calculated by calculating the average score of reading items. The composite score approximates a person's visual ability. The score is calculated using Massof's algorithm using the inverse hyperbolic tangent equation. For the composite score, a lower score is better.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Composite Score-2.095 Score on a Scale
Secondary

VA LV VFQ-48--Item Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 (most difficult) and \>=-2.22 (least difficult). Scores out of this range indicate something other than visual impairment is governing the patient's responses. The Item Score is the average functional reserve of all the items in the questionnaire excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons). Functional reserve is the difference between a patient's visual ability and the visual ability needed to perform an activity.

Time frame: 3 months

Population: Only one subject completed this outcome measure during the 3 month follow-up due to study timeline constraints.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Item Score2.063 Score on a Scale
Secondary

VA LV VFQ-48--Item Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 (most difficult) and \>=-2.22 (least difficult). Scores out of this range indicate something other than visual impairment is governing the patient's responses. The Item Score is the average functional reserve of all the items in the questionnaire excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons). Functional reserve is the difference between a patient's visual ability and the visual ability needed to perform an activity.

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Item Score1.955 Score on a Scale
Secondary

VA LV VFQ-48--Reading Domain Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The reading domain score is calculated by calculating the average score of reading items. Scores range from 0 to 3.5 logits, with higher scores denoting better ability to perform activities. The Reading Domain Score is the average functional reserve of the items measuring the reading functional domain, excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons).

Time frame: 3 months

Population: Only one subject completed this outcome measure during the 3 month follow-up due to study timeline constraints.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Reading Domain Score2.673 Score on a Scale
Secondary

VA LV VFQ-48--Reading Domain Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The reading domain score is calculated by calculating the average score of reading items. Scores range from 0 to 3.5 logits, with higher scores denoting better ability to perform activities. The Reading Domain Score is the average functional reserve of the items measuring the reading functional domain, excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons).

Time frame: Baseline, 2 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Reading Domain ScoreBaseline1.839 Score on a ScaleStandard Deviation 1.05
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Reading Domain Score2 Months2.230 Score on a ScaleStandard Deviation 0.982
Secondary

VA LV VFQ-48--Reading Domain Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The reading domain score is calculated by calculating the average score of reading items. Scores range from 0 to 3.5 logits, with higher scores denoting better ability to perform activities. The Reading Domain Score is the average functional reserve of the items measuring the reading functional domain, excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons).

Time frame: 6 months

Population: The study's start was delayed due to COVID so only 1 participant was able to complete the 6 month follow-up within the grant time frame.

ArmMeasureValue (NUMBER)
Virtual Reality (VR) Treatment--Deficit EyeVA LV VFQ-48--Reading Domain Score2.549 Score on a Scale
Secondary

Veterans Affairs Low Vision Visual Function Questionnaire-48 (VA LV VFQ-48)--Item Score

The VA LV VFQ-48 is a self-report instrument designed to measure difficulty visually impaired persons have performing daily activities. The acceptable range for the average item score is \<= 2.34 (most difficult) and \>=-2.22 (least difficult). Scores out of this range indicate something other than visual impairment is governing the patient's responses. The Item Score is the average functional reserve of all the items in the questionnaire excluding items which were rated Unscored (Difficult / don't do for Non-Visual Reasons). Functional reserve is the difference between a patient's visual ability and the visual ability needed to perform an activity.

Time frame: Baseline, 2 months

ArmMeasureGroupValue (MEAN)Dispersion
Virtual Reality (VR) Treatment--Deficit EyeVeterans Affairs Low Vision Visual Function Questionnaire-48 (VA LV VFQ-48)--Item ScoreBaseline1.248 Score on a ScaleStandard Deviation 0.898
Virtual Reality (VR) Treatment--Deficit EyeVeterans Affairs Low Vision Visual Function Questionnaire-48 (VA LV VFQ-48)--Item Score2 Months1.704 Score on a ScaleStandard Deviation 0.948
Other Pre-specified

Color Vision Test

Change in the percentage of correctly identified trials for each color.

Time frame: First visit after the completion of rehabilitation (1 or 2 months)

Other Pre-specified

Grating Acuity Test

Change in the percentage of correctly identified trials.

Time frame: First visit after the completion of rehabilitation (1 or 2 months)

Other Pre-specified

Shape Recognition Test

Change in the percentage of correctly identified trials.

Time frame: First visit after the completion of rehabilitation (1 or 2 months)

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026