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Analysis of Biomarkers in Lymph Node Tissue

Analysis of Biomarkers in Lymph Node Tissue

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04228796
Enrollment
200
Registered
2020-01-14
Start date
2020-01-06
Completion date
2029-01-01
Last updated
2026-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analysis of Biomarkers in Lymph Node Tissue

Brief summary

Researchers are doing an exploratory analysis of biomarkers to correlate with treatment outcome of transplant surgery.

Detailed description

Researchers will study previously collected tissue, which was sent for pathological examination, of 200 patients who underwent transplant surgery. Concentration of biomarkers in lymph node tissue will be measured.

Interventions

None listed

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults (18+years of age) * Undergo any organ transplant

Exclusion criteria

* Under the age of 18 years old

Design outcomes

Primary

MeasureTime frameDescription
List of biomarkersBaselineImmunohistochemistry (IHC) for the LYVE1, VEGFR3 expression, VEGF-A/C/D, Ki-67, MMP-9 and TIMP-1

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORAntonio Forte, MD, PhD

Mayo Clinic

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026