Elderly, Model, Pain Assessment, Postoperative Pain
Conditions
Brief summary
This study will collect perioperative pain-related data of elderly patients in multi-centers. Analyzing these collected data to find the high-risk factors of postoperative pain in elderly patients and to establish an early-warning model of perioperative pain in elderly patients, so as to improve the ability of assessing the risks of postoperative pain in elderly patients and providing an early warning.
Detailed description
This study will collect perioperative pain-related data of elderly patients in multi-centers, including: preoperative general data, intraoperative anesthesia and surgical data, clinical laboratory data, postoperative pain and intervention, postoperative complications and quality of life. Analyzing these collected data to find the high-risk factors of postoperative pain in elderly patients and to establish an early-warning model of perioperative pain in elderly patients, so as to improve the ability of assessing the risks of postoperative pain in elderly patients and providing an early warning.
Interventions
None listed
Sponsors
Chinese PLA General Hospital
First Affiliated Hospital of Guangxi Medical University
Zhejiang University
Peking University People's Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years or older * Undergoing general or regional anesthesia * Hospitalized for at least 24 hours after surgery * Able to give informed consent * Able to read and write
Exclusion criteria
* Existing diagnoses of psychiatric or neurologic pathology * A history of substance abuse * Admitted to ICU after surgery * Patients with advanced tumors who have received preoperative chemotherapy or who are expected to receive postoperative chemotherapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain trajectories after surgery | within 6 months | The pain trajectory is the vector of mean pain severity domain score (from 0 to 10) measured with pain severity domain of the Revised American Pain Society Patient Outcome Questionnaire (APS-POQ-R) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Outcome of 6-mins-walking test | 1, 3, 7, 14, 21, 30, 60, 90, 120, 150 and180 days postoperation | Walking distance of 6 minutes |
| Number of readmission within 30 days after surgery | Up to 30 days postoperation | Readmission indicates unplanned readmission after hospital discharge. |
| Complications within 30 days after surgery | Up to 30 days postoperation | Complications within 30 days after surgery will be classified using Clavien-Dindo Classification of Surgical Complications, ranging from Grade I(Any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions) to Grade V(death of a patient). |
| Postoperative duration of stay in hospital | 30 days postoperation | The duration when patients stay in hospital after surgery. |
| Ambulation time | Up to 30 days postoperation | The first time when patients can get off of bed and walk after surgery |
| Oral feeding time | Up to 30 days postoperation | The first time when patients begin oral feeding after surgery |
| The trajectories of health related quality of life(HRQoL) | 1, 3, 7, 14, 21, 30, 60, 90, 120, 150 and180 days postoperation | The trajectory of HRQoL is the vector of Utility values measured with EuroQol five-dimensional questionnaire(EQ-5D)taken over 6 months(days 1, 3, 7,14, 21, 30, 60, 90, 120, 150,180; Day 0 is the day of surgery). The EQ-5D measures health on five domains (mobility, self-care, usual activities, pain discomfort, and anxiety-depression), and the scores will be combined using Chinese general population weights to generate a single utility or index score. Utility values for the EQ-5D range from 1.00 to -0.391, where a score of 0 and 1 are regarded as equivalent to death and 'perfect health', respectively, and a score \< 0 is considered as health state that is 'worse than death'. |
Countries
China
Contacts
Primary ContactFeng Yi, MD, PhD
Outcome results
None listed