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Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education

Re-infection Rates of Soil-transmitted Helminth Infections Among School-aged Children Following a Single or a 4-monthly Health Hygiene Education: an Open Label Clinical Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04227834
Enrollment
432
Registered
2020-01-14
Start date
2019-03-04
Completion date
2020-03-02
Last updated
2020-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ascaris Infection, Children, Only, Helminthiasis, Hookworm Infections, Trichuris Infection

Keywords

Soil-transmitted helminth, School-aged children, Health hygiene, Education

Brief summary

Soil-transmitted helminth (STH) infections caused by Ascaris lumbricoides, Trichuris trichiura, or hookworm, affect approximately 1.5 millions individuals primarily in tropical and subtropical regions. STHs infections have been associated with delay in growth and development in children. The prevalence in Indonesia varied from 45% to 65%, but in poor sanitation areas the prevalence can increased to 80%. World Health Organization currently recommends mass treatment with benzimidazoles and health hygiene education to control the disease. In this study we evaluated the effectiveness of single and four-monthly health hygiene education to STH reinfection rates among school-aged children in Mandailing Natal district, North Sumatera province, Indonesia.

Detailed description

In this study we evaluate the prevalence of STH among school-aged children using Kato Katz examination prior to enrolment to the study. Two elementary schools in Mandailing Natal district, North Sumatera province, Indonesia have been selected and received either a single or repeated health hygiene education. Preliminary knowledge was also assessed using a questionnaire. Infected children received treatment of albendazole 400 mg for 3 days. Evaluation on reinfection status and STH knowledge is done at 4 month, 8 month and 12 months.

Interventions

BEHAVIORALHealth hygiene education

A cartoon video explaining the etiology, risk factors, clinical symptoms, treatment and prevention of helminthiasis were given to the school-aged children

Sponsors

Universitas Sumatera Utara
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
6 Years to 15 Years
Healthy volunteers
Yes

Inclusion criteria

* Children who are negative for STHs infection on Kato Katz examination following 3 days treatment of albendazole

Exclusion criteria

* Parents who refused to participate in the study * Severe malnutrition * Co-infected with other helminth infections

Design outcomes

Primary

MeasureTime frameDescription
The effectiveness of repeated health hygiene education on the reinfection rates of STHs among school-aged children12 monthsSTH prevalence at 12 months

Secondary

MeasureTime frameDescription
Prevalence of STHs among school-aged children prior to interventionSTH prevalence at month 0Ascaris lumbricoides, Trichuris trichiura, hookworm infections at month 0
Knowledge of STHs prevention measures among school-aged children before and after intervention12 monthsA questionnaire used to evaluate the knowledge about STHs prevention

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026