Spine Cancer, Spine Disease, Spine Metastases, Thoracic Cancer, Thoracic Diseases, Thoracic Neoplasms
Conditions
Keywords
Thoracic lesions, Lumbar lesions, Sacral spine lesions, MRI Coil, spine radiotherapy, Memorial Sloan Kettering Cancer Center, 19-476
Brief summary
Participants will receive an MRI with a custom-built MRI coil for each participant. The purpose is to find out whether this custom-built MRI coil can help doctors see the different parts of the spine as well as or better than they can with standard CT myelograms.
Interventions
DIAGNOSTIC_TESTMRI with custom MRI spine coil
Participants will undergo MRI with custom MRI spine coil
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \>/= 18 years of age at the time of treatment * Able to give informed consent * Consented for spine stereotactic radiation therapy * No contraindications for CT myelograms which include: * Allergy to CT contrast * Use of phenothiazines * Platelet count \< 60,000 K/mcl * INR \> 1.5 * VEGF inhibitor use in the past 2 weeks prior to myelogram * NSAID use in the past 5 days prior to myelogram * Renal disease * Creatinine \> 1.2 mg/dL * No contraindications for MRI scans which include: * Newly placed glucose monitors * Tattoos (Tattoos for radiation therapy are allowed) * Presence of a cardiac pacemaker * Presence of an implanted cardioverter defibrillator * Breast tissue expander * Aneurysm clip * Any other implanted metallic (BB, bullet, shrapnel, IUD, metallic stent or filter, spinal cord simulator etc.) or electronic device which is considered MR unsafe * Severe claustrophobia or inability to lie flat for the duration of the study, etc.
Exclusion criteria
* Presence of surgical spine hardware at the region of interest * Presence of cervical spine lesions * History of claustrophobia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference of calculated doses to the cauda equine and spinal cord based upon MRI coil vs CT myelogram used to define each structure | 6 months | The calculated doses to the cauda equine and spinal cord will be compared and evaluated for significant difference based upon the imaging modality (MRI coil vs CT myelogram) used to define each structure, with all other target and avoidance volumes being equal in the same patient. |
Countries
United States
Outcome results
None listed