Associations Between Vision and Brain Function

Quantitative Assessment of the Vison Using Structural and Functional Indicators and Associations With Brain Function

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04226729

Enrollment

200

Registered

2020-01-13

Start date

2022-01-25

Completion date

2023-04-30

Last updated

2022-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, Vision; Disorder, Loss

Brief summary

Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess ocular features using structural and functional indicators and define its associations with brain development and intelligence in children.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

3 Years to 12 Years

Healthy volunteers

Yes

Inclusion criteria

* age from 3 to 12 years old

Exclusion criteria

* diagnosed with nervous system disease before

Design outcomes

Primary

Measure	Time frame	Description
the visual information processing function	recorded at enrollment	collected with the electroencephalogram
best corrected visual acuity	recorded at enrollment	collected with visual acuity chart

Secondary

Measure	Time frame	Description
refractive status	recorded at enrollment	the refractive status of both eyes
intraocular pressure	recorded at enrollment	the intraocular pressure of both eyes
fundus picture	recorded at enrollment	the fundus pictures of both eyes

Countries

China

Contacts

Primary ContactYifan Xiang, M.D

565098660@qq.com18826234461

Backup ContactHaotian Lin, M.D,Ph.D

haot.lin@hotmail.com13802793086

Outcome results