Evaluation of the Presence of Enthesitis in Patients With Acne Vulgaris

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04224597

Enrollment

Registered

2020-01-13

Start date

2020-02-01

Completion date

2020-04-01

Last updated

2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris, Enthesitis, Ultrasonography

Keywords

enthesitis, acne vulgaris, Guess

Brief summary

Acne vulgaris is an inflammatory disease of the pilosebaceous unit, affecting about 85% of the young population. In the studies p. acne is a potent stimulator of the release of IFN-gamma (IFN-)) and IL-17 from CD4 + T cells, and the presence of IL-17 + cells in the perifollicular infiltrate has been shown in biopsies of inflammatory acne lesions. Therefore, acne is thought to be a Th17-related disease (1). This study was aimed to evaluate the presence of enthesitis in patients with acne vulgaris.

Detailed description

Patients with acne vulgaris and healthy controls aged between 18-25 who admitted to Hitit University Erol Olcok Education and Research Hostpital Dermatology policlinic will be icluded. Patients with rheumatic, neurological diseases, history of trauma and previous fractures will be excluded from the study. After all the participants were evaluated by the dermatologist and demographic data will be recorded, the participants will be examined by the physical medicine and rehabilitation specialist and the short form-36 (sf-36), hospital anxiety and depression scale will be completed. Bilateral lower extremity tendon thicknesses and the presence of erosion, bursitis, etc. will be evaluated according to the criteria of Guess (Glasgow Ultrasound Enthesitis Scoring System) and Guess score will be determined for all participants. A total of 48 participants, 24 patients with acne vulgaris and 24 healthy controls, will be included in the study (2).

Interventions

DIAGNOSTIC_TESTultrasonography

all participants will be determined by ultrasonography.

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

Inclusion Criteira: * Patients with acne vulgaris and healthy controls aged between 18-25

Exclusion criteria

* Participants with rheumatic and neurologic disease, history of trauma ,

Design outcomes

Primary

Measure	Time frame
patellar tendon thicknesses of patients with acne vulgaris and healthy controls	3 months
Ashilles tendon thicknesses of patients with acne vulgaris and healthy controls	3 months

Countries

Turkey (Türkiye)

Contacts

Primary ContactDilek E Büyükşireci

dilekeker55@gmail.com+905439196253

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026