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Diagnostic Performance of a New Method for the Echocardiographic Assessment of Coronary Arteries Abnormalities

Diagnostic Performance of a Rational and Standardized New Method for the Echocardiographic

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04224090
Enrollment
4000
Registered
2020-01-13
Start date
2014-01-01
Completion date
2021-12-01
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Anomaly

Keywords

Coronary arteries abnormalities, Coronary arteries anomaly, Coronary origin from the wrong sinus of Valsalva, Echocardiography

Brief summary

Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and right. To overcome the echocardiographic limitations, the investigators designed, studied and implemented in our Institute a specific echocardiographic-based two-dimensional non-Doppler 4-views approach for the diagnosis of CAA.

Detailed description

The method consisted of 4-CAA-focused specific views, routinely available from any echocardiographic exam: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views. PSAX, the traditional approach, along with the PLAX, and the apical 4/5-chambers views. A hallmark of CAA was considered the absence of a proper visualization of the origin of the coronary arteries from the aortic root. In addition, the presence of the ring sign, visualized from the PLAX was considered as abnormal. This sign is of interest when an aberrant left or right CAA is suspected. A coronary artery originating from the contralateral aortic sinus, along its intramural course, crosses the mid-anterior line of the circular aorta to reach the sinus of Valsalva of its intended origin. Consequently, its cross-section should be visible in an orthogonal view traversing the mid-long axis of the aorta, namely the parasternal long-axis view.

Interventions

DIAGNOSTIC_TESTEchocardiographic assessment of coronary arteries origin and proximal course

Echocardiographic assessment of CAA utilizing 4 specific echocardiographic acoustic windows: parasternal short-axis (PSAX), parasternal long-axis (PLAX), apical 4/5-chambers views.

Sponsors

Ospedali Riuniti Ancona
CollaboratorOTHER
ITAB - Institute for Advanced Biomedical Technologies
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* patients undergoing their first echocardiographic examination

Exclusion criteria

* already known congenital heart disease and cardiomyopathies

Design outcomes

Primary

MeasureTime frameDescription
CAAAt the time of the routine echocardiography assessmentThe number of coronary arteries anomalies echocardiographically detected

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 16, 2026