ACS - Acute Coronary Syndrome, Oncology
Conditions
Keywords
Cardio-Oncology, Interventional Cardiology, Cancer, Oncology, Acute Coronary Syndrome, Myocardial Infarction
Brief summary
The BRAVADO Registry pretends to identify stratification, diagnosis, total atherosclerotic burden and treatment approaches in oncologic patients with Acute Coronary Syndrome (ACS) and identify strategies to improve health care quality
Interventions
None listed
Sponsors
Instituto do Cancer do Estado de São Paulo
Beneficência Portuguesa de São Paulo
Instituto de Cardiologia do Rio Grande do Sul
InCor Heart Institute
University of Sao Paulo General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Definitive cancer diagnosis - biopsy * Acute Coronary Syndrome - requiring urgent invasive risk stratification
Exclusion criteria
* KPS \< 60 , ECOG \>/ 3 * Life expectancy less 24hs * End of Life Care * Lack of consistent record data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major adverse cardiovascular events | 30 days | Composite endpoint of All-cause Death, Myocardial Infarction, Stroke and Myocardial Revascularization |
| Total Atherosclerotic burden and lesion complexity on angiography | 30 days | The number and location of coronary lesions with obstructions greater than 50% were recorded. Each lesion was classified based on Ambrose's, Goldstein complexity, Leaman and SYNTAX scores. |
| Incidence of Major Bleeding | 30 days | Requiring a transfusion of ≥2 U PRBCs Resulting in a decrease in hematocrit of ≥10% Occurring intracerebrally Resulting in stroke or death |
Countries
Brazil
Outcome results
None listed