Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04220879

Acronym

Enrollment

Registered

2020-01-07

Start date

2019-11-25

Completion date

2020-11-24

Last updated

2020-01-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, Malignant Glaucoma

Keywords

Malignant Glaucoma, Biometric Measurements

Brief summary

In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma. Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography. To analyze the high risk factors and the possible pathogenesis of the disease and discuss the long-term effect of different treatment methods.

Detailed description

Outcome Measures: Anterior chamber depth (ACD) and width (ACW), lens vault (LV), ciliary process-ciliary process distance(CCD), trabecular-ciliary processes distance (TCPD), ciliary body max thickness (CBMT), peripheral iris thickness (PIT), trabecular ciliary process angle (TCPA), and anterior vault (AV), were measured by ultrasound biomicroscopy. Other parameters measured by A-scan ultrasonography and optical coherence tomography.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

(1) history of operation, (2) diagnosis of MG, and (3) eyes with clear optical media.

Exclusion criteria

(1)hypertension or diabetes and (2) diagnosis of ocular fundus diseases.

Design outcomes

Primary

Measure	Time frame	Description
Trabecular ciliary process angle	baseline	TCPA is measured with its apex at the scleral spur, one arm along the posterior corneal surface, and another arm along the most anterior surface of the ciliary body
Choroidal vascularity parameter	baseline	Choroidal vascularity parameter is a vessel ratio measured by optical coherence tomographic images

Countries

China

Contacts

Primary ContactDingqiao O Wang, M.D

wangdingqiao@163.com020-66615461

Backup ContactChengguo O Zuo, M.D,Ph.D

chengguozuo@163.comwangdingqiao@163.com

Outcome results