Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis

Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis : a Retrospective Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04219176

Enrollment

Registered

2020-01-06

Start date

2002-01-23

Completion date

2018-01-02

Last updated

2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Toxoplasmosis

Keywords

Spectral optical coherence tomography, Ocular toxoplasmosis, Uveitis

Brief summary

Ocular toxoplasmosis is the most common cause of infectious uveitis worldwide. The diagnosis of ocular toxoplasmosis is primarily clinical when it is a typical presentation .With an atypical presentation in the fundus, parasitological diagnosis is a decisive contribution, as well as multimodal imaging. We investigate on vitreal, retinal, and choroidal morphologic changes in active and scarred toxoplasmosis lesions using swept source optical coherence tomography.

Detailed description

A retrospective analysis of patients diagnosed with ocular toxoplasmosis was conducted. The patients were examined at ophthalmology service of Farhat Hached Hospital in Sousse Tunisia between January 2002 and December 2017. Complete ophthalmologic examination and OCT were done at the initial visit and during follow-up.

Interventions

DIAGNOSTIC_TESTSpectral optical coherence tomography

Swept-source optical coherence tomography (SS-OCT) is the latest milestone in retinal and choroidal imaging. Because its wavelength of 1050 nm, which is superior to the 840 nm of spectral domain optical coherence tomography (SD-OCT), it is able to overcome ocular opacities such as cataracts and vitritis, wich allows retinal and choroidal visualization of eyes whose fundus is not clearly visible. Consequently , SS-OCT allows visualization of the retinal and choroidal vascular networks, even in eyes with medium opacity

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* all patients hospitalized for ocular toxoplasmosis.

Exclusion criteria

* patients with non active ocular toxoplasmosis

Design outcomes

Primary

Measure	Time frame	Description
number of prticipant affected with ocular toxoplasmosis	up to one year	patient diagnosed having ocular toxoplasmosis

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026