Epidermolysis Bullosa
Conditions
Brief summary
Hereditary Epidermolysis Bullosa (EBH) are rare dermatologic diseases characterized by cutaneous and mucosa fragility. Oral manifestations of few small cohort have been published. The main objective of this multicentric cohort study first in Europe was to report the oral status of these patients that were consulted in the MRDRC of this disease in Nice (France), Toulouse (France) and Louvain (Belgium). Then a correlation between the oral characteristics and the EBH type will be made, in order to facilitate the management of patient care and the prevention program that can be established to improve their oral health.
Interventions
OTHERclinical exam
clinical oral examination
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
7 Months to 78 Years
Inclusion criteria
* patient with EBH * patient consent for examination and use the clinical data for publication purpose
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dental structural abnormalities and/or caries | 1 day | number of defect /dental caries dor each toth |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| gingival biotype | 1 day | clinical observation of gingiva (thin or thick) |
| gingival status | 1 day | observation and classification of the gingiva (healthy, inflammed or hyperplastic) |
| plaque and gingival index | 1 day | registration of plaque and gingival index according to the Loë and Silness method |
| oral lesion | 1 day | number and localisation of the blister/scars/flanges scars on a sketch of a mouth |
Countries
France
Outcome results
None listed