Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome

Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome: Two Arm Randomized Double Blind Placebo Controlled Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04215380

Acronym

GA&PCO

Enrollment

Registered

2020-01-02

Start date

2020-01-25

Completion date

2020-06-15

Last updated

2020-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Brief summary

To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum

Detailed description

Polycystic ovary syndrome (PCOS) affects 5-20% of women of reproductive age worldwide it increases the risk for type 2 diabetes mellitus, cerebrovascular and cardiovascular events and not to mention it is one of the main causes of infertility. in the management of PCOS life style modification like weight reduction is necessary and recently it was discovered that GA ingestion causes significant reduction in BMI and body fat percentage among healthy adult females.so if GA could also affect the hormones and the metabolic changes in PCOs is going to be useful in decreasing the comorbidities and even treating PCOs.

Interventions

DIETARY_SUPPLEMENTAcacia Senegal extract

Oral Digestion of Gum Arabic dissolved in 200 ml of water to be consumed early morning in daily basis for 12 weeks

DIETARY_SUPPLEMENTPectin

Oral Digestion of Pectin to be consumed early morning in daily basis for 12 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Patients who are diagnosed with PCO by independent Gynecologist

Exclusion criteria

* Diabetic patients * Menopausal women * History of allergy to Gum Arabic

Design outcomes

Primary

Measure	Time frame	Description
hormonal changes	12 weeks	Measure changes from the baseline values regarding LH, FSH, and testosterone level

Secondary

Measure	Time frame	Description
Metabolic change Serum cholestrol	12 weeks	Measure decrease from the baseline values regarding serum cholesterol level
Metabolic change HBA1C	12 weeks	Measure decrease from the baseline values regarding HBA1c
Body Mass index	12 weeks	Measure decrease from the baseline values regarding BMI

Countries

Sudan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026