Placenta Previa, Placenta Accreta, Placenta Increta, Placenta Percreta
Conditions
Brief summary
The rotational thromboelastogram (ROTEM) test can be performed on patients with placenta previa/accreta/increta/percreta who have a high likelihood of massive bleeding, and the predictors can be identified by comparing the patients who actually show massive bleeding with those who do not. Applying these predictive factors to pregnant women undergoing cesarean section after diagnosis of placenta previa/accreta/increta/percreta, it will be advantageous for the perioperative management because it is possible to select pregnant women with a factor of massive bleeding.
Interventions
DIAGNOSTIC_TESTROTEM
ROTEM including INTEM, EXTEM, APTEM, and FIBTEM
Sponsors
Seoul National University Bundang Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Cesarean section under spinal anesthesia * Placenta previa * Placenta accreta * Placenta increta * Placenta percreta
Exclusion criteria
* Coagulopathy * Medication with antiplatelets or anticoagulants
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood loss | 1 min after finishing an operation | Volume of intraoperative blood loss |
| Change of INTEM | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation | intrinsic pathway component |
| Change of EXTEM | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation | extrinsic pathway component |
| Change of APTEM | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation | fibrinolytic component |
| Change of FIBTEM | 10 min after spinal anesthesia, 5 min after baby delivery, 1 min after finishing operation | the level of fibrinogen |
Countries
South Korea
Outcome results
None listed