COPD
Conditions
Brief summary
Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.
Detailed description
Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD).
Interventions
OTHERReceived negative pressure ventilation
Patients who received a negative pressure during inspiratory phase.
Sponsors
Fu Jen Catholic University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with COPD who received pulmonary rehabilitation program with NPV treatment
Exclusion criteria
* Recent exacerbation within 3-months * Existing of tracheostomy * Absence of NPV used * Required of oxygen supplement during NPV * Diagnosed of neuromuscular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| CO (cardiac output) | 20 minutes | Change of Cardiac output before and after NPV treatment |
| SV (stroke volume) | 20 minutes | Change of stroke volume before and after NPV treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| SpO2 | 20 minutes | Change of oxygen saturation before and after NPV treatment |
| RR (respiratory rate) | 20 minutes | Change of respiratory rate before and after NPV treatment |
Countries
Taiwan
Outcome results
None listed