Single-port Video-assisted Thoracoscopic Surgery
Conditions
Keywords
Non Small Cell Lung Cancer, Perioperative Efficacy, multi-port
Brief summary
Video-assisted thoracoscopic surgery (VATS) has been widely used for non-small cell lung cancer (NSCLC) for nearly two decades. Usually, it was applied through three ports with at least one drainage after surgery, which often lead to acute chest pain. Therefore, fewer, smaller ports, and wider intercostal space for surgery has been required. Uniport VATS became a feasible option with the development of surgical techniques and instruments, with potentially less postoperative pain and shorter hospital stays. However, there may be some complications, or with a longer time of operation, even more difficult in lymph nodes resection during learning curve. In our study, a Randomized Controlled Trial was designed to study the operation time, perioperative blood loss, conversion rate, duration of postoperative drainage, length of hospital stay, visual analogue score of postoperative pain, complications, and survival.
Interventions
PROCEDUREuniport video-assisted thoracoscopic surgery
video-assisted thoracoscopic surgery for NSCLC using single port or two ports or three ports
PROCEDUREtwo ports video-assisted thoracoscopic surgery
video-assisted thoracoscopic surgery for NSCLC using two ports
PROCEDUREthree ports video-assisted thoracoscopic surgery
video-assisted thoracoscopic surgery for NSCLC using three ports
Sponsors
The Second Hospital of Shandong University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
25 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
patients with cT1-3N0-1M0 NSCLC; good cardiopulmonary function; prepared to undergo radical resection;
Exclusion criteria
patients with N3 or M1 NSCLC; poor cardiopulmonary function; not be prepared to undergo radical resection;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complications | up to 3 months | complications in rate |
| length of hospital stay | within 5-7 days | length of hospital stay in days |
| visual analogue score of postoperative pain | within 5-7 days | score |
| operative time | 1 day | operative time in minutes |
| perioperative blood loss | 1 day | perioperative blood loss in milliliter |
| conversion rate | 1 day | conversion rate in proportion |
| duration of postoperative drainage | within 5-7 days | duration of postoperative drainage in days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| progression- free survival | up to 5 years | progression- free survival in rate |
| overall survival | up to 5 years | overall survival in rate |
Countries
China
Contacts
Primary ContactYunpeng Zhao, Doctor
Outcome results
None listed