Cardiovascular Diseases, Hypertension
Conditions
Keywords
Hypertension, Cardiovascular Diseases, Mortality, Biomarker
Brief summary
Hypertension is the most common chronic diseases and a most important risk factor for cardiovascular and cerebrovascular diseases, and also a substantial public health problem. The purpose of the study is to investigate the association between biomarkers and adverse outcomes in patients with hypertension.
Detailed description
Study population includes subjects who are hypertension, of any race or ethnicity, 18 or older years of age, and have provided written informed consent to provide whole blood specimens at one or more study visits. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.
Interventions
OTHERNon-interventional study
This is an observational, non-interventional study
Sponsors
Guangdong Provincial People's Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥18 years old * In accordance with the diagnosis of hypertension (including Blood pressure ≥140/90mmHg and/or taking antihypertensive drugs and/or self-reported hypertension)
Exclusion criteria
* \<18 years old * Unsigned informed consent * Pregnant Women and Lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-Cause Mortality | From date of inclusion until the date of death from any cause, assessed up to 1 year | All-cause mortality was confirmed through a combination of hospital medical records, telephone contacts with patients or family members, and death registration at the Guangdong Provincial Center for Disease Control and Prevention. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular Mortality | From date of inclusion until the date of death from any cause, assessed up to 1 year | Cardiovascular mortality was defined as death attributable to an ischemic cardiovascular cause (including fatal MI, stroke). |
Other
| Measure | Time frame | Description |
|---|---|---|
| Secondary outcomes of cardiovascular diseases | Through study completion, an average of 1 years | The number of and the incidence rate of cardiovascular diseases. |
| Secondary outcomes of cerebrovascular diseases | Through study completion, an average of 1 years | The incidence rate of cerebrovascular diseases. |
| Secondary outcomes of kidney | Through study completion, an average of 1 years | The incidence rate of hypertensive renal injure and end-stage renal disease |
| others | From date of inclusion until the date of first event, assessed up to 1 year | Number of participants with reported hospitalization due to other diseases(eg. diabetes， tumor) |
Countries
China
Contacts
Primary ContactFeng Ying-qing, PhD
Backup ContactHUANG Yu qing, MD
Outcome results
None listed