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Central Venous Catheters in Pediatric Anesthesia and Intensive Care

Central Venous Catheters in Pediatric Anesthesia and Intensive Care: Prospective Observational Trial

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04211116
Acronym
PEDCVC
Enrollment
107
Registered
2019-12-26
Start date
2020-03-01
Completion date
2021-02-15
Last updated
2021-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Line

Keywords

Central line, Pediatric patient, Insertion, Cannulation

Brief summary

Securing the intravenous line is one of the fundamental interventions in paediatric anaesthesia and intensive care. Central venous catheters (CVC) are indicated for long-term stay in intensive care unit (ICU), in case of circulatory instability and the need for vasopressor therapy, for hypertonic solutions administration and parenteral nutrition. The dominant method of CVC insertions is the Seldingers´ method (over the wire) and ultrasound real-time navigation in recommended. Ultrasound-guided (USG) CVC insertion however requires experience personnel and relevant training.This could be the main reason, that CVC the real-time ultrasound navigation is still not adequately implemented into the clinical practice.

Detailed description

After Ethics committee approval, patients indicated for CVC insertions will be included. Based on the observational design of the trial, the method of insertion (Real-time ultrasound navigation versus anatomical-based CVC insertion) will be based on operators´ decision.The indication for CVC insertion, primary planned site of insertion, USG implementation, site of actual CVC cannulation and associated complications will be recorded. The primary aim of the study was to compare the effectivity of Real-time ultrasound navigation versus anatomical-based CVC insertion in paediatric patients and the 1st percutaneous puncture success rate. The secondary aims will be the incidence of associated complications and the time form first percutaneous puncture, to definitely securing the CVC in place. The primary hypothesis is that the Ultrasound-guided CVC insertion is superior, with the higher overall success, higher first attempt success rate and with lower incidence of associated complications.

Interventions

DEVICECentral venous line insertion

Pediatric patients indicated to central venous line insertion

Sponsors

Brno University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 19 Years
Healthy volunteers
No

Inclusion criteria

* Pediatric patients within the age limit indicated for CVC insertion

Exclusion criteria

* Outside the age limit

Design outcomes

Primary

MeasureTime frameDescription
Overall success and first attempt success rateDuring CVC insertionThe overall success rate and first attempt success rate will be evaluated between ultrasound-guided and anatomical-based navigation

Secondary

MeasureTime frameDescription
Incidence of complications24 hours from CVC insertionIncidence of arterial puncture, hemothorax and/or pneumothorax incidence, incidence of CVC malposition will be recorded
Time of insertionDuring CVC insertionThe time from first percutaneous puncture to CVC insertion will be monitored and evaluated between

Countries

Czechia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026