Cleave-stage Transfer on Day 3 Versus Day 5 Transfer When Only One Embryo Available

Transfer of Single Embryo on Day 3 or 5 When Only One Embryo Transfer

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04210414

Acronym

Cleave-blast

Enrollment

Registered

2019-12-24

Start date

2020-01-10

Completion date

2021-11-10

Last updated

2022-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

When only one embryo is available after in vitro fertilization, the option is to transfer either day 3 or day 5. There is no randomized trial compared the day 3 to day 5 for this subgroup.

Detailed description

Recruitment is very slow. The TSC will discuss termination next meeting with the DMC.

Interventions

OTHEREmbryo transfer

Transfer of only one embryo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 42 Years

Healthy volunteers

Inclusion criteria

* Infertile couple with only one embryo available for transfer

Exclusion criteria

* ineligible for study

Design outcomes

Primary

Measure	Time frame
Ongoing pregnancy rate	within 20 weeks of gestation

Secondary

Measure	Time frame
Biochemical pregnancy rate	One month
clinical pregnancy	7 weeks of gestation
Embryo development after In vitro fertilization cycle	6 days after in vitro fertilization

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026