Endometriosis, Endometriosis; Bowel, Endometriosis, Rectum, Endometriosis-related Pain
Conditions
Brief summary
To describe the difference in patient reported outcomes after conservative treatment in comparison to radical rectal surgery in patients with deep endometriosis infiltrating the rectum (up to 15cm from the anus with at least involvement of the muscularis layer) and to determine predictors for radical surgery.
Interventions
OTHERPROMS
Patient Reported Outcomes after different types of surgery for rectal endometriosis
Sponsors
Universitaire Ziekenhuizen KU Leuven
Semmelweis University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Inclusion criteria
* Age: 18 - 45 years (both inclusive) * BMI \<35 * Complaining of infertility and/or pain * Deep endometriosis infiltrating the rectum on at least one imaging technique up to 15 cm from the anus and involving at least the muscularis layer in depth
Exclusion criteria
* Refusal of bowel resection/stoma * History of laparotomy for endometriosis * (history of) Hysterectomy * Suspected pelvic malignancy * Pregnancy * Impossibility for postoperative follow-up in our hospital
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The proportion of patients experiencing one of the following symptoms at 12 months postoperatively: | 12 months postoperatively | * constipation (1 stool/\>5 consecutive days) * frequent bowel movement (≥3 stools/day) * defecation pain * anal incontinence (involuntary loss of gas or stools) * dysuria * bladder atony requiring self-catheterization |
| The determination of possible risk factors for radical surgery. | 3 months postoperatively | based on patient complaints, preoperative imaging techniques and intra operative finding |
Countries
Belgium, Hungary
Contacts
PRINCIPAL_INVESTIGATORCarla Tomassetti, MD, PhD
UZ Leuven
Outcome results
None listed