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To Explore the Related Factors of Cough After Thoracoscopic Pneumonectomy

Multivariate Analysis of Cough After Uniport Video-assisted Thoracoscopic Surgery Pneumonectomy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04204148
Enrollment
120
Registered
2019-12-18
Start date
2019-12-01
Completion date
2020-04-30
Last updated
2019-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough

Keywords

postoperative cough, Multivariate analysis, non-small cell lung cancer (NSCLC), Uniport Video-assisted Thoracoscopic Surgery

Brief summary

To explore the related factors of cough after Uniport video-assisted thoracoscopic surgery pneumonectomy, and to provide theoretical basis and social accumulation of new knowledge for the diagnosis and treatment of cough after pneumonectomy in the future.

Detailed description

Intractable cough after thoracoscopic pneumonectomy is one of the common complications after pneumonectomy. The incidence of cough can reach 25% ≤ 50%. Cough after operation can aggravate the pain of incision, prolong the hospitalization time, increase the cost of hospitalization, affect the conversation and even sleep of the patients, increase the psychological burden of the patients, and reduce the quality of life of the patients accordingly. Therefore, through this study, the investigators hope to understand the related factors of cough after thoracoscopic pneumonectomy and whether there are predictable risk factors, so as to provide theoretical basis for reducing the occurrence of cough after pneumonectomy.

Interventions

None listed

Sponsors

The First Affiliated Hospital of Soochow University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 years old, male and female * Uniport video-assisted thoracoscopic surgery * No cough symptoms within two weeks before operation * Informed consent form was signed before operation

Exclusion criteria

* Diabetes , heart, brain, liver and kidney diseases * Chest radiographs / CT in recent months indicate pneumonia * Pulmonary function cannot tolerate lobectomy / segmental / cuneiform resection * Distant metastasis patients * Before operation, there were internal causes of cough (including respiratory tract infectious diseases, pharyngitis, allergic rhinitis, posterior nasal drip syndrome, etc.)

Design outcomes

Primary

MeasureTime frameDescription
The mean Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC) score before and after surgeryThe day before surgery,two weeks after surgery,one month after surgeryThe Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC), which assesses the cough-related quality of life, consists of 19 items divided into three domains: the physical (8 items), psychological (7 items) and social (4 items) domains. A 7-point Likert scale was used to score individual domains. The total scores ranged from 3 to 21, with a higher score indicative of a better health status

Secondary

MeasureTime frameDescription
Hospitalization daysFrom the first days after surgery to discharge,up to 4 weeksThe numbers of days of patients stay in the hospital after surgery
DrainageMeasure the volume every 24 hours,up to 4 weeksThe total volume of fluid
Anesthesia timeRecord total anesthesia during surgeryTime from patient anesthesia to extubation

Countries

China

Contacts

Primary ContactJun Zhao
zhaojia0327@126.com13906130266
Backup ContactChang Li
cli@suda.edu.cn15295666957

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026