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Implementation and Effectiveness of Multidiscipline-Integrated Addiction Treatment Model

Implementation and Effectiveness of Multidiscipline-Integrated Addiction Treatment Model

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04203654
Enrollment
48
Registered
2019-12-18
Start date
2020-02-24
Completion date
2020-12-15
Last updated
2020-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amphetamine-Related Disorders

Keywords

Methamphetamine, Cognitive behavior group therapy

Brief summary

Management of substance use disorders in clinical settings is challenging. Approaches with integrated bio-psycho-social interventions, along with the engagement of families and self-help groups are strongly recommended. The Matrix intensive outpatient program has been developed in UCLA to help the psychostimulant misusers in the Southern California in 1980's. With integration of the existing evidence of addiction researches and empirically supported cognitive-behavior treatment techniques, the Matrix model developed manuals to address knowledge and skills needed for drug users in their early recovery and relapse prevention. The treatment was delivered in a 16-week intensive structured group sessions. There was also a 12-week educational sessions for the in-treatment individuals and their families. A substantial body of evidence has demonstrated the successful experience of the Matrix treatment model in management a broad spectrum of addictive disorders in many countries. The objectives of the pilot project are to set up a multi-center collaborative clinical network with implementation of an integrated addiction treatment program modified from the UCLA Matrix model. Via the establishment of standardized subject recruitment criteria, treatment and outcome assessment procedures, the study aims to assess the adherence of participating clinical organizations to the study protocol, the acceptance of participating MA misusers for the integrated treatment program as well as the outcomes and their determinants for the treatment models.

Detailed description

Methamphetamine (MA) use disorder is a serious legal and health problem worldwide. Reports from Ministry of Justice in Taiwan revealed that the MA-related crimes has tremendously increased over the past decade. The arrested users of scheduled II drugs, MA mainly, has surged from 34,886 in 2014 to 54,190 in 2016 in Taiwan. It is critical to tackle the emerging problems in Taiwan. Management of MA use disorder in clinical settings is challenging. Approaches with integrated bio-psycho-social interventions, along with the engagement of families and self-help groups are strongly recommended. The Matrix intensive outpatient program has been developed in UCLA to help the psychostimulant misusers in the Southern California in 1980's.With integration of the existing evidence of addiction researches and empirically supported cognitive-behavior treatment techniques, the Matrix model developed manuals to address knowledge and skills needed for drug users in their early recovery and relapse prevention. The treatment was delivered in a 16-week intensive structured group sessions. There was also a 12-week educational sessions for the in-treatment individuals and their families. A substantial body of evidence has demonstrated the successful experience of the Matrix treatment model in management a broad spectrum of addictive disorders in many countries. The objectives of the pilot project are to set up a multi-center collaborative clinical network with implementation of an integrated addiction treatment program modified from the UCLA Matrix model. Via the establishment of standardized subject recruitment criteria, treatment and outcome assessment procedures, the study aims to assess the adherence of participating clinical organizations to the study protocol, the acceptance of participating MA misusers for the integrated treatment program as well as the outcomes and their determinants for the treatment models.

Interventions

cognitive-behavior group therapy Frequency: thrice a week Treatment duration: 16 week

Individual supportive psychotherapy 3 sessions during the 16-week treatment period

Sponsors

National Health Research Institutes, Taiwan
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Aged 20-65 * Current methamphetamine use disorder by DSM-5, moderate and above * Willing and able to provide informed consents

Exclusion criteria

* Severe physical or psychiatric conditions requiring emergent treatment * Currently involved in judicial or criminal conditions * Plan to go abroad or relocate in the next 6 months

Design outcomes

Primary

MeasureTime frameDescription
Urine amphetamine test During Intervention16 weeksThis test looks for amphetamine in urine once a week for 16 weeks.
Urine amphetamine test,Follow-Up3 monthsThis test looks for amphetamine in urine once a month for 3 months.

Secondary

MeasureTime frameDescription
The World Health Organization Quality of Life -BREF (WHOQOL-BREF) During Intervention16 weeksThe content of the questionnaire is divided into four domains. The converted scores of each participant's answers are as low as 4 points and as high as 20 points in each category,a higher score means better quality of life.
The World Health Organization Quality of Life -BREF (WHOQOL-BREF),Follow-Up3 monthsThe content of the questionnaire is divided into four domains. The converted scores of each participant's answers are as low as 4 points and as high as 20 points in each category,a higher score means better quality of life.

Countries

Taiwan

Contacts

Primary ContactSheng-Chang Wang, Doctor
scwang69@gmail.com+886-37-206-166

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026