Multi-country, Multi-center Cohort Study of Anti-Mullerian Hormone Profile in Asia Pacific Infertile Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04203355

Enrollment

4000

Registered

2019-12-18

Start date

2020-01-01

Completion date

2021-05-31

Last updated

2019-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

This study is to detect the infertile couple (women) Anti-Mullerian Hormone (AMH) profile in major subgroups such as Poly Cystic Ovarian Syndrome (PCOS), Endometriosis, etc via age intervals and ethnic difference.

Detailed description

To consecutively enroll infertile couple (women) who are undergoing their first controlled ovarian stimulation cycles. To mainly compare the inter-ethnic difference in age-specific AMH profile in unexplained infertility, male factor infertility, PCOS, Endometriosis etc. subgroups. To detect the influence of past or present smoking on age-specific AMH levels To study the influence of body mass index (BMI) on age specific AMH levels

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 43 Years

Healthy volunteers

Yes

Inclusion criteria

* Diagnosed as infertile couple * Naive patients who plan to enter their first ovarian stimulation cycles * Women among 20-43 years old

Exclusion criteria

* Systematic disease that impact AMH (eg. systemic lupus erythematosus (SLE), Crohn's disease etc.) * Chemotherapy history * Alcohol abuse * Currently taking oral contraceptive pills

Design outcomes

Primary

Measure	Time frame	Description
Anti-mullerian hormone level in general population	within 3 months before controlled ovarian stimulation cycles	Inter-ethnic difference in age-specific AMH level

Secondary

Measure	Time frame	Description
Anti-mullerian hormone level in PCOS patients	within 3 months before controlled ovarian stimulation cycles	AMH level in PCOS patients vs non-PCOS patients in age-specific intervals
Anti-mullerian hormone level in endometriosis patients	within 3 months before controlled ovarian stimulation cycles	AMH level in endometriosis patients vs non-endometriosis patients in age-specific intervals

Countries

China, Hong Kong, India, Indonesia, Japan, Malaysia, Philippines, South Korea, Taiwan, Thailand, Vietnam

Contacts

Primary ContactChii-Ruey Tzeng, MD, Ph.D

tzengcr@tmu.edu.tw+88 622 737 2181

Outcome results