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Oropharyngeal Exercises and Inspiratory Muscle Training in Obstructive Sleep Apnea

Comparison of the Effectiveness of Inspiratory Muscle Training and Oropharyngeal Exercises in Patients With Obstructive Sleep Apnea Syndrome: a Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04201236
Enrollment
41
Registered
2019-12-17
Start date
2019-04-01
Completion date
2019-10-01
Last updated
2019-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Keywords

obstructive sleep apnea, oropharyngeal exercises, inspiratory muscle training, sleep quality

Brief summary

The effects of orofarangeal exercises (OE) and inspiratory muscle training (IMT) on sleep quality, disease severity, and airway muscle tone have been investigated in several studies. IMT and OE exercise modalities for patients and practitioners have advantages and disadvantages. It is recommended to compare exercise modalities in the studies. Whether OE or IMT exercise type is more effective on disease severity, sleep quality and snoring has not been investigated. The aim of this study was to compare the effectiveness of inspiratory muscle training and oropharyngeal exercises in patients with OSAS in terms of disease severity, snoring, daytime sleepiness, respiratory muscle strength and sleep quality.

Interventions

OTHERrespiratory muscle strengthening exercise

These exercises strengthen locally inspiratory muscles. IMT can be done with threshold loaded devices.

OTHERoropharyngeal muscles strengthening exercise

These exercises strengthen locally oropharyngeal muscles. Oropharyngeal exercise can be done with some facial movements .

Sponsors

Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
19 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

\*To be diagnosed with mild, moderate and severe OSAS.

Exclusion criteria

* Patients with a history of stroke, * neurological disease, * severe obstructive nasal disease, * and infection in the last month, * BMI being 40 kg /m2 or more.

Design outcomes

Primary

MeasureTime frameDescription
Polysomnography2 daySleep efficiency, apnea-hypopnea index (AHI). Higher sleep efficiency and lower AHI values shows that patient have better status and lower disease severity

Secondary

MeasureTime frameDescription
6 minute walk test2 dayExercise capacity
Epworth Sleepiness Scale2 dayminimum and maximum scores: 0-24. The higher the ESS score, the higher that person's average sleep propensity in daily life (ASP), or their 'daytime sleepiness'
Berlin Questionnaire2 daySnoring frequency (0-3) and severity (0-4). Higher scores show higher snoring frequency and severity
Maximal inspiratory and expiratory muscle strength measurement with mouth pressure device6 dayRespiratory muscle strength
The Pittsburgh Sleep Quality Index2 daySleep quality. Minimum and maximum scores: 0-21. Higher scores show worse sleep quality
Fatigue Severity Scale2 dayFatigue severity. Minimum and maximum scores: 0-7. Scores higher than 4 shows high intensity fatigue perception
Functional Outcomes of Sleep Questionnaire2 dayQuality of life related with sleep. Minimum and maximum scores: 0-16. Higher scores show worse sleep related quality of life

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026