Neonatal Infection, Pre-Term
Conditions
Keywords
cardiac output; echocardiography; USCOM; neonates
Brief summary
Non-invasively neonatal cardiac output can be measured by multiple methods, but the gold standard still remains conventional echocardiography. It is accurate, but needs a long training for new users to assess cardiac function. Continuous-wave Doppler ultrasound monitor USCOM is a relatively new monitor which can perform faster and less complex cardiac function measurement, also it is easier for the operator to get trained. The aim of the study is to assess the level of agreement between cardiac output measured with conventional echocardiography and with USCOM, to present normal ranges for neonates of different gestational age and to look for early signs of hemodynamic changes during sepsis.
Interventions
DEVICEUltrasound Cardiac Output Monitor (USCOM 1A)
doplerometry with USCOM and echocardiograph is made for assessing central blood flow and spectroscopy with NONIN- for the blood flow in individual peripheral organs (brain and kidney)
Sponsors
Vilnius University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
26 Weeks to 44 Weeks
Healthy volunteers
Yes
Inclusion criteria
* newborns of any gestational age * parental consent acquired
Exclusion criteria
* congenital malformations * hemodynamic instability in control group * any respiratory support in control group * infection in control group
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Weight measurement | 1 minute | weight in grams |
| Height measurement | 1 minute | length in centimeters |
| Chest and head circumference | 1 minute | Chest and head circumference in centimeters |
| Blood pressure measurement | 1 minute | non- invasive arterial blood pressure measurement in mmHg |
| Pulse rate measurement | 1 minute | pulse rate in beats per minute |
| Near- Infrared Spectroscopy for regional blood flow | 15-20 minutes | One sensor on the forehead, another- on the back to check for regional blood flow in the brain and kidney with Near- Infrared Spectroscopy |
| Echocardioscopy for left ventricular outflow tract diameter | 2-3 minutes | Echocardiography for left ventricular outflow tract diameter in centimeters |
| Echocardioscopy to measure velocity time integral | 3 minutes | Echocardiography to measure velocity time integral at the aortic valve in centimeters. After that the software of the device calculates cardiac output. |
| USCOM examination | 3-5 minutes | USCOM 1A uses continuous wave Doppler for flow curves, which are obtained at the suprasternal notch for an optimal flow signal at the aortic valve. The software of the device calculates cardiac output then |
Countries
Lithuania
Outcome results
None listed