Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria

Definition of Acute Respiratory Distress Syndrome in Plateau of Qinghai in China: Verification of Berlin Definition Plateau Criteria

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04199650

Enrollment

253

Registered

2019-12-16

Start date

2019-04-01

Completion date

2020-08-30

Last updated

2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS, High Altitude

Brief summary

The severity stratification criteria for acute respiratory distress syndrome (ARDS) in Xi'ning Qinghai province (mean altitude: 2200m) were clarified according to the oxygenation index (PaO2/FiO2).

Detailed description

This study is a single-center retrospective study. According to the Berlin diagnostic standard, ARDS patients admitted to the Department of severe Medicine, affiliated Hospital of Qinghai University from January 2018 to December 2018 were divided into three groups: mild (153mmHg \< PaO2/ FiO2 ≥ 230 mmHg), moderate (76mmHg \< PaO2/ FiO2 ≥ 153 mmHg) and severe (PaO2/ FiO2 ≥ 76 mmHg). The ICU mortality, 28-day mortality, non-ventilator time in ICU, ICU hospitalization time and non-I hospitalization were observed respectively. The difference of CU time and total hospitalization days.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years of age * Meet the diagnostic criteria of ARDS * Receive invasive mechanical ventilation

Exclusion criteria

* Receive a large number of hormone shock therapy in a short period of time * Death within a short period of time (\< 24 h) after mechanical ventilation * No chest imaging data * Data missing

Design outcomes

Primary

Measure	Time frame	Description
ICU mortality	up to 24 weeks	Mortality during treatment in ICU
28-days mortality rate	28 days after discharge	Mortality at 28 days of hospitalization

Secondary

Measure	Time frame	Description
Ventilator Free time	up to 24 weeks	Ventilator time not used in ICU
Ventilator time	up to 24 weeks	Ventilator time in ICU
Hospital length of stay	up to 24 weeks	Total length of stay in hospital

Countries

China

Contacts

Primary ContactGan Guifen, Bachelor

xzhd1991@163.com15897083336

Backup ContactPan Chun, Doctor

panchun1982@gmail.com13814009925

Outcome results