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Impulse Control in Gilles de la Tourette Syndrome

Do Mirror Neurons Play a Role in Tourette Syndrome Physiopathology? A Pilot Study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04197804
Enrollment
40
Registered
2019-12-13
Start date
2018-05-02
Completion date
2019-04-30
Last updated
2023-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tourette Syndrome

Brief summary

The study intends to evaluate the role of Mirror Neurons in the determination of gestures, words, and repetitive vocalizations in subjects affected by Tourette's syndrome and to verify if these subjects are faster to assemble sounds, in phonology and morphology, than the non-pathological population.

Interventions

OTHERRoutine tests perform

The subjects of the Tourette group and control group are subjected to routine tests performed at Tourette Center and Extrapyramidal Diseases. Both groups are initially subjected to an evaluation that aims to identify the IQ and therefore 4 tasks are presented. The 1st (with a duration of about 2 and a half minutes) and the 2nd (with a duration of about 2 minutes) related to the motor field, the 3rd (with duration of about 1 minute) and the 4th (with duration about 3 minutes) the language field. These evaluations are in practice at the Center for Tourette patients; the tasks will be administered to both groups.

Sponsors

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Years to 10 Years
Healthy volunteers
Yes

Inclusion criteria

TOURETTE GROUP * Consecutive patients belonging to the Tourette Center * Caucasian * Italian mother-tongue * Age between 6 and 10 years completed * Male and female 4: 1 (16 males and 4 females) * Diagnosis of Tourette's syndrome for at least 1 year * Presence of a value of YGTSS\> 50% NOT GROUP TOURETTE * Caucasian * Italian mother-tongue * Age between 6 and 10 years completed * Male and female 4: 1 (16 males and 4 females)

Exclusion criteria

TOURETTE GROUP * Diagnosis of DSA * Presence of significant psychiatric disorders, with the exception of those belonging to the Tourette Syndrome itself (eg ADHD, OCD). NOT GROUP TOURETTE * Diagnosis of DSA * Presence of significant psychiatric disorders

Design outcomes

Primary

MeasureTime frameDescription
Tourette syndrome and the imitation of gesturesThrough study completion, an average of 1 yearThe aim is to investigate the correlation between Mirror Neurons and Tourette Syndrome defining the greater propensity of the Tourettian subjects to imitate gestures, through the administration of the first Task

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026