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Management of Acutely Symptomatic Hernia

Management of Acutely Symptomatic Hernia: An Observational Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04197271
Acronym
MASH
Enrollment
280
Registered
2019-12-13
Start date
2020-03-03
Completion date
2021-03-24
Last updated
2021-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hernia, Emergencies, Surgery--Complications

Keywords

outcome, hernia, emergency

Brief summary

Acutely symptomatic abdominal wall hernia can cause many symptoms and complications. They can be associated with levels of morbidity beyond that seen in emergency laparotomy. There is limited data to guide practice in this field. This observational cohort study will explore variation in practice around assessment, repair and outcomes of hernias treated in the emergency setting.

Detailed description

There are many different types of hernia, with the most common being in the groin or at the umbilicus. Hernias affect a significant proportion of the population and can vary from producing no symptoms at all, to causing a blockage to the bowel that requires urgent surgery. Hernias affect people of all ages and degrees of health, but become increasingly common with age. As our population ages and therefore becomes generally more unwell, the risks of surgery increase. Recent evidence suggests that emergency hernia repair is associated with worse outcomes than planned procedures. At present there are limited guidelines for the management of acutely symptomatic hernias and therefore practice varies between hospitals. This cohort study will capture information on patients treated in the UK for acutely symptomatic hernia, and will provide information on variation in assessment, and technical aspects of repair. It will also capture health utility data out to 90 days post discharge from hospital.

Interventions

Emergency repair of hernia using method selected by treating surgeon.

Treatment of hernia without resort to surgery

Sponsors

Sheffield Teaching Hospitals NHS Foundation Trust
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients aged 18 years and over * Patients admitted directly to the emergency surgery service (via A+E or GP) * Patients referred to the emergency surgical team by another inpatient specialty * Patients with a diagnosis of an acutely symptomatic hernia made by a specialist surgical trainee (ST3+) or Consultant Surgeon * Willing to take part in the study

Exclusion criteria

* Patients under 18 years of age * Pregnant women * Patients with a symptomatic parastomal, hiatal or diaphragmatic hernia * Patients with a traumatic hernia * Unable to consent

Design outcomes

Primary

MeasureTime frameDescription
In hospital morbidityup to 28 days after surgeryAs defined using the comprehensive complication index

Secondary

MeasureTime frameDescription
Change in health utilityMeasured at baseline, 30 days post discharge and 90-days post recruitmentMeasured using EQ-5D-5L questionnaire
MortalityMeasured at baseline, 30 days post discharge, and 90 days post recruitmentDeath occuring (binary)
Hospital length of stayWithin 30 days of recruitment to studyTime from admission to discharge measured in days
Unplanned readmission within 30 daysUp to 30 days of recruitmentUnplanned readmission to hospital for any reason following treatment of hernia

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026