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Risk Assessment for Prolonged Sickness Absence Due to Musculoskeletal Conditions

Risk Assessment for Prolonged Sickness Absence Due to Musculoskeletal Conditions

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04196634
Enrollment
560
Registered
2019-12-12
Start date
2018-11-01
Completion date
2023-09-30
Last updated
2023-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Pain Disorder

Keywords

Risk Assessment

Brief summary

Musculoskeletal (MSK) conditions are a leading cause of years lived with disability worldwide and for the last decade they have also been the most common cause of sickness absence and disability pension in Norway. Although most sickness absence is short-termed, a small proportion of people with MSK conditions are on long-term sick leave, contributing to large cost due to disbursement of benefits, productivity loss and extensive use of health care. There is growing evidence that long-term sickness absence is harmful to mental and physical health, with a reduced probability of return to work (RtW) with prolonged sickness absence. Thus, focusing on early RtW in people on sick leave due to MSK conditions is important to reduce the burden on both the individual and the society. However, to provide interventions to reduce the duration of sickness absence to all people on sick leave would require enormous resources. By targeting those at risk of long-term sickness absence, resources may be used differently, e.g. more resource-saving. By using information on modifiable risk factors from simple risk assessment tools, health care providers and other stakeholders may facilitate RtW in a better way. The overall purposes of this project are 1) to identify the most accurate screening tool to identify people at a high risk of prolonged sickness absence due to a MSK condition, and 2) to investigate severity of MSK health, health-related quality-of-life, health care consumption, and costs across different risk profiles in people on sick leave due to MSK conditions. We will use registered data on sickness absence from 1 year before to 1 year after inclusion in the study.

Detailed description

Main aims are: * To compare the predictive ability of the STarT MSK tool and the ÖMPSQ-SF, and other established risk factors for long-term sickness absence (e.g. symptoms of depression and emotional distress, low motivation for returning to work, low self-efficacy, work expectancies) for identifying prolonged sickness absence at 6- and 12-months follow-up due to MSK conditions * To develop a prognostic model to predict risk of prolonged sickness absence at 12-month follow-up in people with MSK conditions * To assess predictors for high costs (productivity loss and health care use) at 6- and 12-months follow-up in people on sick leave due to MSK conditions The study will also include additional methodological and descriptive aims. Prior to the data collection we translated and culturally adapted the Keele STarT MSK and MSK-HQ following the Beaton guidelines. The study is conducted within the Norwegian Welfare and Labor Administration (NAV) system in collaboration with OsloMet - Oslo Metropolitan University. Data on sickness absence from the NAV registry will be retrieved prospectively in the period from study inclusion to 12 months follow-up, and retrospectively 12 months prior to inclusion in the study. Previous studies show that 30-40% of people with MSK conditions have not RtW after 3 to 12 months. In order to conduct analyses including 15- 20 predictor variables, we aim at including 500-600 people on sick leave due to MSK conditions. As the main outcomes are collected through registries, we do not expect any dropouts.

Interventions

OTHERRisk assessment

People on sick leave due to musculoskeletal conditions will be screened for potential risk factors for prolonged sickness absence. No intervention will be given.

Sponsors

Norwegian Labour and Welfare Administration
CollaboratorOTHER
Oslo Metropolitan University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* People older than 18 years on sick leave due to musculoskeletal pain for at least 4 weeks

Exclusion criteria

* People on sick leave for other pain conditions or diseases * People not able to read or write Norwegian or English

Design outcomes

Primary

MeasureTime frameDescription
Sickness absence days12 monthsTotal number of absence days during 12 months of follow-up adjusted for percentage of work and percentage of sickness absence. Register data from the national health and welfare services
Sickness absence costs12 monthsSickness absence costs will be calculated based on data from the NAV registry
Health care costs12 monthsUse of health care will be collected from public registries including Norwegian Patient Registry (NPR), Municipal Patient and User Registry (KPR) and Control and Payment of Health Refunds (KUHR).
Proportion who have returned to work12 monthsProportion of people with sustainable return to work (at least 4 weeks) at 12 months. Register data from the national health and welfare services
Probability of return to work12 monthsProbability of working (i.e. not receiving medical benefits) each month during 12 months of follow-up, measured as repeated events. Register data from the national health and welfare services
Time to sustainable return to work12 monthsThe time until full sustainable return to work, i.e. at least 4 weeks without relapse during 12 months of follow-up. Register data from the national health and welfare services

Secondary

MeasureTime frameDescription
Sickness absence days6 monthsTotal number of absence days during 6 months of follow-up adjusted for percentage of work and percentage of sickness absence. Register data from the national health and welfare services
Musculoskeletal Health Questionnaire (MSK-HQ)Baseline and 4 weeks14 questions scored on a 0-4-point scale, summed up to a 0 to 56 points score, with higher score indicating better musculoskeletal health.
EuroQol 5 Dimensions (EQ5D-5L)Baseline and 4 weeksThe EQ5D-5L covers five domains: mobility, self-care, activities of daily living, pain/discomfort, and anxiety/depression, scored on a 5-point scale from 0 (worst imaginable health) to 5 (best imaginable health). Responses can be transformed into an index ranging from -0.59 to 1, where -0.59 represents worst possible state and 1 represents perfect health. The EQ5D Visual Analogue Scale (VAS) is also included, which is a question asking about the respondent's self-rated health on a vertical 0 to 100 visual analog scale, with 100 being best health.
Institute of Medical Technology Assessment (iMTA) Productivity Cost Questionnaire (iPCQ)Baseline and 4 weeksMeasure and value health-related productivity loss for both paid and unpaid work. The instrument is found to be suitable for measuring absenteeism from paid work and productivity loss related to unpaid labor. Nine questions related to paid work and three questions related to unpaid work.
Time to sustainable return to work6 monthsThe time until full sustainable return to work, i.e. at least 4 weeks without relapse during 6 months of follow-up. Register data from the national health and welfare services
Proportion who have returned to work6 monthsProportion of people with sustainable return to work (at least 4 weeks) at 6 months. Register data from the national health and welfare services
Probability of return to work6 monthsProbability of working (i.e. not receiving medical benefits) each month during 6 months of follow-up, measured as repeated events. Register data from the national health and welfare services
Health care costs6 monthsUse of health care will be collected from public registries including Norwegian Patient Registry (NPR), Municipal Patient and User Registry (KPR) and Control and Payment of Health Refunds (KUHR).
Sickness absence costs6 monthsSickness absence costs will be calculated based on data from the NAV registry

Other

MeasureTime frameDescription
Change in condition4 weeks7-point global rating of change: Could you please state the amount of change concerning your musculoskeletal symptoms compared to when you first filled out this questionnaire. Answered with: Much better / Better / Slightly better / Unchanged / Slightly worse / Worse / Much worse
Work conflictBaseline and 4 weeksSingle question on work conflict: Did you experience conflict(s) with your employer before you got sick-listed? (Yes/No)
Örebro Musculoskeletal Pain Screening Questionnaire short form (ÖMPSQ -sf)Baseline and 4 weeksÖMPSQ-sf contains 10 questions that are summed up to 0 to 100 score, with higher score indicating higher risk developing work disability.
Demographic variablesBaselineGender, age, diagnosis
Keele STarT MSK Screening toolBaseline and 4 weeksThe STarT MSK consists of 10 items and the scores are summarized to a 0-12 score, with risk groups being categorized as follow: 0-4= low risk; 5-8= medium risk; 9-12= high risk of developing long-term pain or disability.
Return to work expectancyBaseline and 4 weeksMeasured with a single question: For how long do you believe you will be sick listed from today? Answered with: Not at all / Less than 1 month / 1-2 months / 2-4 months / 4-10 months / More than 10 months
Work abilityBaseline and 4 weeksMeasured with a single question from the Work Ability Index: Assume that your work ability at its best has a value of 10 ponts. How many points would you give to your current work ability? Measured on a numeric rating scale where 0 means that you cannot currently work at all, 10 means that your work ability is at its best right now.
Work satisfactionBaseline and 4 weeksMeasured with a single question: If you take into consideration your work routines, management, salary, promotion possibilities and work mates, how satisfied are you with your job? Measured on a numeric rating scale, 0=Not satisfied at all, 10=Completely satisfied Measured with a single question: Do you want to return to the same work/position or do you wish you had another work/position? Answered with: Same work/position / Another work/position.

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 22, 2026