Cirrhosis, Liver, HCC
Conditions
Keywords
CT
Brief summary
Patients with liver cirrhosis is at risk of developing HCC. To diagnose or detect HCC at CT/MRI, optimal late arterial phase (LAP) acquisition is critical to capture the tumor. For LAP acquisition, bolus-tracking is often used at CT. In patients with portal hypertension, however, bolus-tracking occasionally capture early arterial phase which may be related with slow portomesenteric flow. In this study, we obtain dual arterial phase in patients with suspected portal hypertension and determine whether this protocol (dual arterial phase) would provide higher incidence of LAP acquisition than single arterial phase acquisition.
Interventions
DIAGNOSTIC_TESTLiver CT
Liver CT with precontrast, dual arterial phase, portal venous phase, and delayed phase.
Sponsors
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Older than 20 years * Liver cirrhosis diagnosed with characteristic imaging feature or histology * Presence of portal hypertension sign (splenomegaly and varices) * Scheduled for liver CT * And signed informed consent
Exclusion criteria
* Relative or absolute contra-indication of contrast-enhanced CT
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of optimal late arterial phase acquisition | 1 months after study completion | incidences of optimal late arterial phase acquisition in 1st and 2nd acquisition of arterial phase in this protocol (dual arterial phase) CT. |
Countries
South Korea
Outcome results
None listed