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Chest Dysphoria in Transmasculine Spectrum Adolescents

The Effect of Top Surgery on Chest Dysphoria in Assigned-Female-At-Birth, Transmasculine Spectrum Youth and Young Adults

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04195659
Enrollment
81
Registered
2019-12-12
Start date
2019-10-29
Completion date
2021-12-31
Last updated
2022-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gender Dysphoria

Brief summary

The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in assigned-female-at-birth, transgender and non-binary youth and young adults. This is a prospective, observational study that will enroll assigned-female-at-birth, transmasculine spectrum individuals age 13 to 25 years old who are or are not undergoing top surgery. Participants will complete a set of standard of care questionnaires regarding their chest dysphoria (e.g., distress about the chest), gender dysphoria (e.g., distress about a gender identity that does not match assigned sex), and gender congruence (e.g., degree to which an individual feels they are living in their authentic appearance and gender identity). They will complete this same set of questionnaires either three months after their top surgery or three months after the initial set of surveys.

Interventions

PROCEDUREMastectomy and chest masculinization

A surgical procedure in which the breasts are removed and the chest is given a masculine contour.

Sponsors

Ann and Robert H. Lurie Children's Hospital of Chicago
CollaboratorUNKNOWN
University of Illinois at Chicago
CollaboratorOTHER
Northwestern University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
13 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

* Assigned the female sex at birth * Affirmed gender identity of male, non-binary, or gender other than female * English-speaking * Undergoing top surgery or matches a top surgery participant on age and number of months on testosterone

Exclusion criteria

* Non English speaking * Unable to complete self-report questionnaires

Design outcomes

Primary

MeasureTime frameDescription
Chest DysphoriaThree monthThe disruption of individual comfort, physical functioning, and interpersonal relationships from a chest with breasts, as measured by the Chest Dysphoria Measure (Score 0-51, Higher number means greater chest dysphoria)

Secondary

MeasureTime frameDescription
Gender DysphoriaThree monthDistress about a gender identity that differs from assigned sex, measured by the Utrecht Gender Dysphoria Scale (Score 12-60, Higher number means greater gender dysphoria)
Gender CongruenceThree monthFeelings of living in an authentic gender identity and appearance, as measured by the Kozee Transgender Congruence Scale (Score 12-60, Higher number means greater gender congruence)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026