Olfaction Changes in Patients Undergoing Spine Surgery

Prospective Observational Pilot Study on Olfaction Alterations That Occur in Spine Patients After Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04194788

Enrollment

Registered

2019-12-11

Start date

2021-04-29

Completion date

2021-07-27

Last updated

2023-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic Disorder of Spine, Smell Disorder

Brief summary

This observational prospective study evaluates perioperative olfaction alterations, comprising changes in threshold value, discrimination and identification, which occur in spine patients. The single group is subjected to a preoperative and a postoperative assessment.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* Males or females * Caucasian race * Between 50 and 85 years of age * Candidates to spine surgery * Acceptance and signing of informed consent

Exclusion criteria

* Past or present cancer * Heart failure * Kidney failure (III-IV) * Past or present neuropsychiatric disorders * Heavy smokers (over/equal 3 cigarettes per day) * Smell disorders * Rhinitis * Allergies to the respiratory system

Design outcomes

Primary

Measure	Time frame	Description
Changes in olfaction threshold	Day before surgery and first day after surgery	Changes in the olfaction threshold evaluated with a series of solutions having different concentrations of aromas

Countries

Italy

Outcome results