Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, Spasticity, Local Vibration, Muscle Architecture, Functionality
Brief summary
Gastrocnemius spasticity is one of the main complaints in Multiple Sclerosis patients.Local muscle vibration is a method used for spasticity inhibition. However, when the studies in the literature are examined; It is noted that local vibration applications for spasticity are usually single sessions and evaluate the acute effect, do not produce functional outputs, there is no consensus on frequency and amplitude and the changes in muscle architecture are not examined. In this study, we aimed to investigate the effect of local vibration applied on spastic gastrocnemius on muscle architectural and functional properties in Multiple Sclerosis patients in addition to the standard physiotherapy program. The study was planned to include 3 groups, 2 treatment and 1 control group. The control group will receive standard physiotherapy, one of the treatment groups will receive 50 Hz local vibration in addition to standard physiotherapy, and other treatment group will receive 100 Hz local vibration in addition to standard physiotherapy. Disease severity, gastrocnemius spasticity, architectural and viscoelastic properties of muscle, ankle proprioception, balance and gait skills will be evaluated before and after 8 weeks treatment program. As a result; effectiveness of local vibration in addition to standard physiotherapy program and whether there is a difference between applications at different frequencies will be examined.
Interventions
OTHERStandard physiotherapy program+50 Hz local vibration
Standard physiotherapy program (strength, balance, gait exercises) for 50 minutes and local vibration applied to gastrocnemius (50 Hz) for 10 minutes will be performed 3 days a week for 8 weeks.
OTHERStandard physiotherapy program+100 Hz local vibration
Standard physiotherapy program (strength, balance, gait exercises) for 50 minutes and local vibration applied to gastrocnemius (100 Hz) for 10 minutes will be performed 3 days a week for 8 weeks.
Standard physiotherapy program (strength, balance, gait exercises) for 60 minutes will be performed 3 days a week for 8 weeks.
Sponsors
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* \> 18 years * EDSS\<5,5 * Gastrocnemius spasticity\<2
Exclusion criteria
* having any injury or surgery of the lower extremity * having systemic and metabolic disease * having behavioral and cognitive problems that prevent consistence to guidelines given
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of Muscle Thickness and Fascicle Length with Ultrasonography | 3 minutes | Bilateral Medial Gastrocnemius US evaluations were performed with use of a 5-10 MHz linear probe (Diasus Dynamic Imaging Ltd, Livingston, Scotland,UK). Patients were positioned prone position with their legs and their muscles relaxed for medial gastrocnemius. Muscle Thickness and Fascicle Length would be expressed as centimeters. |
| Evaluation of Pennation Angle with Ultrasonography | 2 minutes | Bilateral Medial Gastrocnemius US evaluations were performed with use of a 5-10 MHz linear probe (Diasus Dynamic Imaging Ltd, Livingston, Scotland,UK). Patients were positioned prone position with their legs and their muscles relaxed for medial gastrocnemius. Pennation Angle would be angularly indicated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of ankle proprioception | 5 minutes | Isokinetic dynamometer (Isomed 2000) (passive ankle joint position sense) |
| Assessment of single leg balance | 3 minutes | Single leg balance test |
| Assessment of spasticity | 5 minutes | Modified Ashworth Scale (minimum score 0 (worse), maximum score 4 (better)) |
| Assessment of gait characterictics | 5 minutes | GAITRite Analysis System (assessment of velocity, step length, percentage of gait cycle spent in double and single support, stance phase, swing phase, base of support) |
| Assessment of balance | 10 minutes | Bertec Balance Check ScreenerTM force platform system (Assessment of limits of stability, anteroposterior and mediolateral sway range) |
| Assessment of viscoelastic properties of muscle | 5 minutes | Myoton-3 (assessment of tone, elasticity and stiffness) |
Countries
Turkey (Türkiye)
Contacts
Primary ContactFatma Ayvat, MSc
Outcome results
None listed