Uterine Fibroid, Myoma;Uterus, Tranexamic Acid Adverse Reaction
Conditions
Keywords
uterin fibroid, laparoscopic myomectomy
Brief summary
This research is planned as a randomised double-blind controlled trial. interventions to reduce haemorrhage during laparoscopic myomectomy for fiboids is important. İntraoperative Tranexamic acid usage can reduce haemorrhage and related symptoms when given during laparoscopic myomectomy. There is no randomised controlled trials in literature about tranexamic acid usage in laparoscopic gynecological operations.
Detailed description
researchers planned this trial by firstly randomising the patients. 1 gr tranexamic acid in 100 ml salin will bi given by initial of the anesthesia of the patient, the other group will be taken only 100ml saline solution. Randomising will be double blind and only anesthesiologist will see if the paient is in working group or control group. Than researchers provide laparoscopic myomectomy with same prothocol to each patient. At the end of the operation, researchers will record all the parameters during operation like; operation starting and ending time, the amount of bleeding, time of suturing, the size, location and count of myoma uteri, complications, weight of myoma uteri and the change of haemoglobine levels before and after operation.
Interventions
1 GR TRANEXAMİC ACİD İN 100 ML SALİNE SOLUTİON GİVEN İN 15 MİNUTES
100 ML SALİNE SOLUTİON
Sponsors
Study design
Intervention model description
PROSPECTİVELY DOUBLE-BLİND RANDOMİSED CONTROLLED TRİAL
Eligibility
Inclusion criteria
* myoma uteri * appropiate for laparoscopy
Exclusion criteria
* malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| amount of bleeding during operation | 0 minute - 180 minute | total amount of bleeding during surgery |
| operation duration time | 0 minute - 180 minute | time between initial and end of the surgery |
Countries
Turkey (Türkiye)