Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC

Two Different Types of Ventilation in Preterm Neonates; Bilevel Volume Guarantee and Pressure Regulated Volume Control

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04191239

Enrollment

Registered

2019-12-09

Start date

2021-01-01

Completion date

2021-06-30

Last updated

2021-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary Dysplasia, Mechanical Ventilation Complication, Newborn Morbidity, Respiratory Failure

Brief summary

Intubated preterm infants between 800-1200 grams and under 32 weeks of gestational age will start with PRVC ventilation mode, basal blood gases and work of breathing will measured. After that mode will shift to Bilevel Volume Guarantee mode for two hours than clinical and other parameters will be checked again. After this intervention, patients will allocated to PRVC or Bilevel VG group for remaining time.

Interventions

DEVICEGE ventilator with two different modes

GE ventilator with two different modes

Study design

Observational model

CASE_CROSSOVER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to 3 Months

Inclusion criteria

* Need for mechanical ventilation * 800-1200 grams of birthweight * Surfactant received * under 32 weeks of gestational age

Exclusion criteria

No need to intubation Congenital anomalies \-

Design outcomes

Primary

Measure	Time frame	Description
Intubation time	8 weeks	Duration of mechanical ventilation

Secondary

Measure	Time frame	Description
Oxygen dependency	8 weeks	Need for supplemantal oxygen

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026