Smoking Cessation, Thoracic Surgery
Conditions
Keywords
Postoperative Pulmonary Complications, Smoking Cessation Intervention
Brief summary
This is a feasibility study of a personalised, integrated smoking cessation in the surgical pathway in patients undergoing major elective thoracic surgery when compared to usual care of standard community/hospital based NHS smoking cessation. Half the patients will receive the intervention and half the patients will receive usual care.
Detailed description
Smoking prior to major thoracic surgery is a major risk factor for development of postoperative complications which effect both short and long-term outcome. Despite this 1 in 5 patients continue to smoke before their operation. Project MURRAY is a trial comparing the effectiveness of personalised integrated smoking cessation delivered by trained health-care practitioners in the thoracic surgical pathway, and is a three part package of behaviour interventions and pharmacotherapy as per National Institute of Clinical Excellence (NICE)/ National Centre for Smoking Cessation Training (NCSCT) guidance which is supported by an adjunct web-based application. This is a pilot study to evaluate feasibility of a substantive trial and study processes in 5 adult thoracic centres including the trial coordinating site at the University Hospitals Birmingham NHS Foundation Trust. This is a multicentre feasibility study, with aim for equal weighting between the two arms of the integrated smoking cessation and an observation only group of usual care.
Interventions
BEHAVIORALIntegrated Behavioural therapy
Integrated smoking cessation behavioural therapy
DRUGIntegrated Pharmacotherapy
Integrated smoking cessation pharmacotherapy including choice of combination nicotine replacement therapy, varenicline or electronic cigarettes
DEVICEIntegrated Web-based application
Integrated smoking cessation web-based application
Sponsors
University College, London
University of Birmingham
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Current tobacco smoker (smoked within the last 28 days) * Major Thoracic Surgery (including both open and minimally invasive approach) * Able to provide written informed consent * At least 1 weeks' time to surgery * Age over 18 years
Exclusion criteria
* Emergency thoracic surgery * Inability to perform exhaled carbon monoxide (CO) measurements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recruitment | 0 days from recruitment | To establish the number of patients who agree to participate in the intervention as a proportion of those eligible to enter the study |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Variability of smoking cessation practices | 0 days from recruitment, 1 day of surgery, 1 month after surgery | To define the variability of smoking cessation practices in all patients using the nicotine replacement usage questionnaire |
| Integration of intervention | 0 days from recruitment, 1 day or surgery | Integration of the intervention into the clinical pathway by time from decision to operate from study recruitment |
| Barriers to recruitment | 0 days from recruitment | Descriptive reasons for non-participation from screening logs |
| Smoking cessation in the usual care group | 1 day of surgery, 1 month after surgery | To assess the proportion of patients in an observation only usual care group who have quit smoking |
| Smoking cessation in the intervention group | 1 day of surgery, 1 month after surgery | To assess the proportion of patients who receive the intervention who have quit smoking |
| Qualitative interview | 1 month after surgery | To understand patients' experience of and engagement with the intervention, and any unintended consequences To establish whether the intervention is acceptable to thoracic surgery patients and staff, and investigate recommendations for optimisation in intervention delivery |
| Fine tune procedures and data capture forms | 0 days from recruitment, 1 day of surgery, 1 month after surgery | To pilot data capture forms aiming for over 90% completion of important perioperative data for each patient |
Contacts
Primary ContactAmy Kerr
Backup ContactSalma Kadiri
Outcome results
None listed