Central Nervous System Vulnerabilities in Preterm Infants
Conditions
Brief summary
Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances. Our aim in this study was to compare brain volume obtained by USG and MRI.
Detailed description
All preterm infants less than 32 weeks of gestational age undergo cranial USG examination routinely at least, in the first week of life, at the end of first month and corrected age 36 weeks and 40 weeks. We will performa all USG mesurements with measureing intracranial hegiht, anteroposterior diameter, biparietal diamater, ventriccular height, thalamo-occipital distance and ventricular index. We will calculate the brain volume as a spheric geometric shape than we will calculate two ventricles as conical shapes. Absolute brain volume will be calculating by substracting two ventricles from total brain volume. At 40 weeks of age we will perform a cranial MRI to show exact brain volume and we will ccompare two different methods.
Interventions
OTHERCranial MRI
Cranial MRI
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 3 Months
Healthy volunteers
No
Inclusion criteria
* All preterm infants under 32 weeks of gestational age and birth weight between 800-1200 grams * Born in our hospital * Alive during discharge
Exclusion criteria
* congenital anomalies * cranial bleeding * early death
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Results of two different brain volumes | 6 months | Patients in cohort will have both USG and cranial MRI |
Countries
Turkey (Türkiye)
Contacts
Primary ContactFUAT EMRE CANPOLAT, MD
Outcome results
None listed