Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation

Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation- A Retrospective Analysis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04188717

Enrollment

253

Registered

2019-12-06

Start date

2010-01-01

Completion date

2017-01-01

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Transplant; Complications, Neurologic Complication, Postoperative Complications

Keywords

liver transplantation, neurological complications, postoperative complications

Brief summary

Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* patients undergoing liver transplant surgery * 18-65 years

Exclusion criteria

* pregnant patients * Acute Liver Failure, Acute on Chronic Liver Failure

Design outcomes

Primary

Measure	Time frame	Description
Neurological complications	90 days	type of neurological complication
Mortality	90 days	mortality due to any cause

Outcome results