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Social Media Intervention for Cannabis Use in Emerging Adults

Social Media Intervention for Cannabis Use in Emerging Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04187989
Enrollment
149
Registered
2019-12-05
Start date
2020-02-03
Completion date
2020-12-18
Last updated
2022-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cannabis Use

Keywords

Social Media

Brief summary

The purpose of the study is to develop and test social media interventions to help young people increase well-being and reduce risky behaviors. The study will help researchers learn about ways to deliver wellness information in a way that is appealing and helpful to young people who use Facebook.

Interventions

Information will be posted by e-coaches. You can interact with the e-coaches as well as other study members in your group.

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
University of Michigan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

* self-report using cannabis at least 3 time per week or more often in the past month * active Facebook profile * view and click on a social media ad

Exclusion criteria

* fail identity verification based on 1) Internet Protocol (IP) addresses, 2) survey time completion, 3) repeat attempts, 4) survey responses, and 5) photo identification via a timestamped selfie sent to the research staff.

Design outcomes

Primary

MeasureTime frameDescription
Frequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)3-months post baseline30-day TLFB self-report will be used to assess total number of days of cannabis use.
Quantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)3-months post baseline30-day Timeline Follow-Back (TLFB) self-report will be used to assess quantity (grams) of cannabis consumed.
Consequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire Using Dichotomous Response Scale as Previously Described Throughout This Trial Registration.3-months post-baselineMarijuana Adolescent Consequences Questionnaire will be used to assess past 3 month consequences of cannabis use. Consequences are measured by report of number of times incidents from the list of 26 items (e.g., quality of work suffered, had less energy, etc.) resulted from cannabis use. Responses will be dichotomized (0 = never, 1= greater than never) and summed for a total score reflecting total number of consequences. Response scale: Never 1-2 times 3-5 times 6-10 times More than 10 times Minimum score =0, maximum = 26. Higher score = more consequences.
Consequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire6-months post-baselineMarijuana Adolescent Consequences Questionnaire will be used to assess past 3 month consequences of cannabis use. Consequences are measured by report of number of times incidents from the list of 26 items (e.g., quality of work suffered, had less energy, etc.) resulted from cannabis use. Responses will be dichotomized (0 = never, 1= greater than never) and summed for a total score reflecting total number of consequences. Response scale: Never 1-2 times 3-5 times 6-10 times More than 10 times Minimum score =0, maximum = 26. Higher score = more consequences.

Secondary

MeasureTime frameDescription
Other Drug Use as Measured by Items Modified From Monitoring the Future Survey3 months post-baselineItems from the Monitoring the Future Survey will be used to assess past 30 day use of 6 other substances - substances used and number of times of use. Response values will be summed for a total score using mid-point of the range scoring. Substances assessed include: hallucinogens, opioids, stimulants, sedatives, lsd, ecstasy Response scale: 0 0 Occasions 1. 1-2 Occasions 2. 3-5 Occasions 3. 6-9 Occasions 4. 10-19 Occasions 5. 20-39 Occasions 6. 40 or More Occasions
Perceived Risk of Cannabis Use as Measured by 2 Modified Items From the Monitoring the Future Survey3-months post-baselineTwo items rating current opinion on a scale from no risk to great risk of their perceived risk harm from occasional cannabis use and regular use. Items are-- How much do you think people risk harming themselves (physically or in other ways), if they: 1. Use marijuana or marijuana products occasionally 2. Use marijuana or marijuana products regularly Response options are: 1. No risk 2. Slight risk 3. Moderate risk 4. Great risk Answers from both items are added together. The total range of two items summed can be 2-8. Higher totals indicate higher perceived risk.
Quantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)3 months post-baseline30-day TLFB self-report will be used to assess the quantity of alcohol consumed.
Frequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)3 months post-baseline30-day TLFB self-report will be used to assess total number of days of alcohol consumption.
Perceived Risk of Cannabis Use as Measured by Modified Items From the Monitoring the Future Survey6-months post-baselineTwo items rating current opinion on a scale from no risk to great risk of their perceived risk harm from occasional cannabis use and regular use. Items are-- How much do you think people risk harming themselves (physically or in other ways), if they: 1. Use marijuana or marijuana products occasionally 2. Use marijuana or marijuana products regularly Response options are: 1. No risk 2. Slight risk 3. Moderate risk 4. Great risk Answers from both items are added together. The total range of two items summed can be 2-8. Higher totals indicate higher perceived risk.
Peer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey3 months post-baselineOne item rating of current perception of whether their close friends would disapprove of their cannabis use (regardless of how much they use), rated as: 1. Not disapprove 2. Disapprove 3. Strongly disapprove
Cannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire3 months post-baselineFive items from the modified Young Adult Driving Questionnaire will be used to assess past 3 month driving under the influence of cannabis. Response values will be summed for a total score. In the PAST 3 MONTHS...how many times did you drive within one hour after using marijuana or marijuana products containing THC? * how many times did you drive while a little high on marijuana or marijuana products containing THC? * how many times did you drive while very high on marijuana or marijuana products containing THC? * how many times did you drive when you knew your use of marijuana/marijuana products containing THC may already have affected your coordination? * how many times did you ride in a car or other vehicle driven by someone who had been using marijuana or marijuana products containing THC? Response options: 0= Never 1. Once 2. Twice 3. 3 times 4. 4 times 5. 5 times 6. 6-9 times 7. 10 or more times

Countries

United States

Participant flow

Recruitment details

There were 2 waves of recruitment: Wave 1 (February 2020) occurred for participants residing in states without legal recreational cannabis; Wave 2 (May 2020) occurred for those living in states with legal recreational cannabis.

Participants by arm

ArmCount
Social Media Intervention
Facebook page that will deliver health information focused on increasing well-being and reducing risky behaviors. Social Media Intervention: Information will be posted by e-coaches. You can interact with the e-coaches as well as other study members in your group.
76
Control
An Attention-Control E-News (control) condition
73
Total149

Withdrawals & dropouts

PeriodReasonFG000FG001
Overall Study - 3-Month Follow-UpLost to Follow-up68
Overall Study - 6-Month Follow-UpLost to Follow-up88

Baseline characteristics

CharacteristicSocial Media InterventionControlTotal
Age, Continuous21.2 years
STANDARD_DEVIATION 2.3
20.9 years
STANDARD_DEVIATION 2
21.0 years
STANDARD_DEVIATION 2.2
Alcohol quantity (total drinks) in past 30 days15.9 estimated standard drinks
STANDARD_DEVIATION 15.6
17.4 estimated standard drinks
STANDARD_DEVIATION 18.3
16.6 estimated standard drinks
STANDARD_DEVIATION 16.7
Alcohol use days in past 30 (from Timeline Follow Back: TLFB)6.2 days
STANDARD_DEVIATION 6.7
7.2 days
STANDARD_DEVIATION 7.2
6.6 days
STANDARD_DEVIATION 6.9
Cannabis-impaired driving11.1 units on a scale
STANDARD_DEVIATION 10.5
9.7 units on a scale
STANDARD_DEVIATION 8.8
10.4 units on a scale
STANDARD_DEVIATION 10.2
Ethnicity (NIH/OMB)
Hispanic or Latino
13 Participants56 Participants69 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
63 Participants17 Participants80 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants
Past 30-day other substance use index2.0 mid-point of range total score across 6
STANDARD_DEVIATION 4.9
1.4 mid-point of range total score across 6
STANDARD_DEVIATION 3.6
1.70 mid-point of range total score across 6
STANDARD_DEVIATION 4.3
Peer approval1.0 units on a scale
STANDARD_DEVIATION 0.2
1.1 units on a scale
STANDARD_DEVIATION 0.3
1.05 units on a scale
STANDARD_DEVIATION 0.3
Perceived risk3.1 units on a scale
STANDARD_DEVIATION 1.1
3.4 units on a scale
STANDARD_DEVIATION 1.1
3.2 units on a scale
STANDARD_DEVIATION 1.1
Race/Ethnicity, Customized
American Indian/Alaska Native
3 Participants1 Participants4 Participants
Race/Ethnicity, Customized
Asian American
3 Participants4 Participants7 Participants
Race/Ethnicity, Customized
Black/African American
8 Participants7 Participants15 Participants
Race/Ethnicity, Customized
Multi-racial
15 Participants14 Participants29 Participants
Race/Ethnicity, Customized
Other race
5 Participants4 Participants9 Participants
Race/Ethnicity, Customized
White
42 Participants43 Participants85 Participants
Sex: Female, Male
Female
43 Participants40 Participants83 Participants
Sex: Female, Male
Male
33 Participants33 Participants66 Participants
Total consequences from Marijuana Adolescent Consequences Questionnaire9.4 count of consequences
STANDARD_DEVIATION 4.8
10.1 count of consequences
STANDARD_DEVIATION 5.8
9.8 count of consequences
STANDARD_DEVIATION 5.3
Total days of cannabis use in past 30 (from Timeline Follow Back: TLFB)20.8 days
STANDARD_DEVIATION 9.3
16.7 days
STANDARD_DEVIATION 11.1
18.8 days
STANDARD_DEVIATION 10.4
Total estimated grams cannabis use from Timeline Follow Back (past 30 days)21.5 grams
STANDARD_DEVIATION 22.3
13.1 grams
STANDARD_DEVIATION 17.6
17.5 grams
STANDARD_DEVIATION 20.6

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 760 / 73
other
Total, other adverse events
0 / 760 / 73
serious
Total, serious adverse events
0 / 760 / 73

Outcome results

Primary

Consequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire

Marijuana Adolescent Consequences Questionnaire will be used to assess past 3 month consequences of cannabis use. Consequences are measured by report of number of times incidents from the list of 26 items (e.g., quality of work suffered, had less energy, etc.) resulted from cannabis use. Responses will be dichotomized (0 = never, 1= greater than never) and summed for a total score reflecting total number of consequences. Response scale: Never 1-2 times 3-5 times 6-10 times More than 10 times Minimum score =0, maximum = 26. Higher score = more consequences.

Time frame: 6-months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionConsequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire9.9 total consequences (count)Standard Deviation 6.5
ControlConsequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire8.8 total consequences (count)Standard Deviation 5.6
p-value: 0.15895% CI: [-0.746, 0.067]t-test, 2 sided
Primary

Consequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire Using Dichotomous Response Scale as Previously Described Throughout This Trial Registration.

Marijuana Adolescent Consequences Questionnaire will be used to assess past 3 month consequences of cannabis use. Consequences are measured by report of number of times incidents from the list of 26 items (e.g., quality of work suffered, had less energy, etc.) resulted from cannabis use. Responses will be dichotomized (0 = never, 1= greater than never) and summed for a total score reflecting total number of consequences. Response scale: Never 1-2 times 3-5 times 6-10 times More than 10 times Minimum score =0, maximum = 26. Higher score = more consequences.

Time frame: 3-months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionConsequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire Using Dichotomous Response Scale as Previously Described Throughout This Trial Registration.10.1 total number of consequences (count)Standard Deviation 5.7
ControlConsequences of Cannabis Use as Measured by the Marijuana Adolescent Consequences Questionnaire Using Dichotomous Response Scale as Previously Described Throughout This Trial Registration.10.2 total number of consequences (count)Standard Deviation 5.7
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.65695% CI: [-0.425, 0.269]t-test, 2 sided
Primary

Frequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess total number of days of cannabis use.

Time frame: 6-months post baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionFrequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)16.8 daysStandard Deviation 12.2
ControlFrequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)15.8 daysStandard Deviation 11.8
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.1495% CI: [-0.092, 0.621]t-test, 2 sided
Primary

Frequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess total number of days of cannabis use.

Time frame: 3-months post baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionFrequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)18.0 daysStandard Deviation 11.5
ControlFrequency of Cannabis Use as Reported on the Timeline Follow-Back (TLFB)14.9 daysStandard Deviation 11.7
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.9895% CI: [-0.478, 0.466]t-test, 2 sided
Primary

Quantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)

30-day Timeline Follow-Back (TLFB) self-report will be used to assess quantity (grams) of cannabis consumed.

Time frame: 6-months post baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionQuantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)15.5 quantity (grams)Standard Deviation 21.7
ControlQuantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)11.5 quantity (grams)Standard Deviation 15
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.72495% CI: [-0.294, 0.421]t-test, 2 sided
Primary

Quantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)

30-day Timeline Follow-Back (TLFB) self-report will be used to assess quantity (grams) of cannabis consumed.

Time frame: 3-months post baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionQuantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)19.8 quantity (grams)Standard Deviation 26.7
ControlQuantity of Cannabis Used as Reported on the Timeline Follow-Back (TLFB)11.6 quantity (grams)Standard Deviation 15.6
Secondary

Cannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire

Five items from the modified Young Adult Driving Questionnaire will be used to assess past 3 month driving under the influence of cannabis. Response values will be summed for a total score. In the PAST 3 MONTHS...how many times did you drive within one hour after using marijuana or marijuana products containing THC? * how many times did you drive while a little high on marijuana or marijuana products containing THC? * how many times did you drive while very high on marijuana or marijuana products containing THC? * how many times did you drive when you knew your use of marijuana/marijuana products containing THC may already have affected your coordination? * how many times did you ride in a car or other vehicle driven by someone who had been using marijuana or marijuana products containing THC? Response options: 0= Never 1. Once 2. Twice 3. 3 times 4. 4 times 5. 5 times 6. 6-9 times 7. 10 or more times

Time frame: 3 months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionCannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire10.2 total of 5 items (range = 0 to 35)Standard Deviation 11.4
ControlCannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire8.8 total of 5 items (range = 0 to 35)Standard Deviation 10.4
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.84995% CI: [-0.381, 0.314]t-test, 2 sided
Secondary

Cannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire

Five items from the modified Young Adult Driving Questionnaire will be used to assess past 3 month driving under the influence of cannabis. Response values will be summed for a total score. In the PAST 3 MONTHS...how many times did you drive within one hour after using marijuana or marijuana products containing THC? * how many times did you drive while a little high on marijuana or marijuana products containing THC? * how many times did you drive while very high on marijuana or marijuana products containing THC? * how many times did you drive when you knew your use of marijuana/marijuana products containing THC may already have affected your coordination? * how many times did you ride in a car or other vehicle driven by someone who had been using marijuana or marijuana products containing THC? Response options: 0= Never 1. Once 2. Twice 3. 3 times 4. 4 times 5. 5 times 6. 6-9 times 7. 10 or more times

Time frame: 6 months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionCannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire9.6 total of 5 items (range 0 to 35)Standard Deviation 11.1
ControlCannabis Impaired Driving as Measured by 5 Items From the Modified Young Adult Driving Questionnaire7.2 total of 5 items (range 0 to 35)Standard Deviation 10.1
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.66795% CI: [-0.607, 0.371]t-test, 2 sided
Secondary

Frequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess total number of days of alcohol consumption.

Time frame: 6 months post-baseline

Population: Number of participants analyzed is due to focus on alcohol drinkers only

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionFrequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)4.9 daysStandard Deviation 7.6
ControlFrequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)6.5 daysStandard Deviation 7.8
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.45795% CI: [-0.273, 0.597]Cohen's D
Secondary

Frequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess total number of days of alcohol consumption.

Time frame: 3 months post-baseline

Population: Number of participants analyzed is due to focus on alcohol drinkers only

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionFrequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)6.0 daysStandard Deviation 8
ControlFrequency of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)6.1 daysStandard Deviation 8.1
Comparison: : We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.60395% CI: [-0.531, 0.311]t-test, 2 sided
Secondary

Other Drug Use as Measured by Items Modified From Monitoring the Future Survey

Items from the Monitoring the Future Survey will be used to assess past 30 day use of 6 other substances - substances used and number of times of use. Response values will be summed for a total score using mid-point of the range scoring. Substances assessed include: hallucinogens, opioids, stimulants, sedatives, lsd, ecstasy Response scale: 0 0 Occasions 1. 1-2 Occasions 2. 3-5 Occasions 3. 6-9 Occasions 4. 10-19 Occasions 5. 20-39 Occasions 6. 40 or More Occasions

Time frame: 3 months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionOther Drug Use as Measured by Items Modified From Monitoring the Future Survey3.4 total of 6 items using mid-point scoringStandard Deviation 7.9
ControlOther Drug Use as Measured by Items Modified From Monitoring the Future Survey1.0 total of 6 items using mid-point scoringStandard Deviation 4.3
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIsp-value: 0.05195% CI: [-0.689, 0.005]t-test, 2 sided
Secondary

Other Drug Use as Measured by Items Modified From Monitoring the Future Survey

Items from the Monitoring the Future Survey will be used to assess past 30 day use of 6 other substances - substances used and number of times of use. Response values will be summed for a total score using mid-point of the range scoring. Substances assessed include: hallucinogens, opioids, stimulants, sedatives, lsd, ecstasy Response scale: 0 0 Occasions 1. 1-2 Occasions 2. 3-5 Occasions 3. 6-9 Occasions 4. 10-19 Occasions 5. 20-39 Occasions 6. 40 or More Occasions

Time frame: 6 months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionOther Drug Use as Measured by Items Modified From Monitoring the Future Survey2.5 total of 6 items using midpoint of rangeStandard Deviation 7.2
ControlOther Drug Use as Measured by Items Modified From Monitoring the Future Survey1.9 total of 6 items using midpoint of rangeStandard Deviation 10.1
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.71495% CI: [-0.412, 0.284]t-test, 2 sided
Secondary

Peer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey

One item rating of current perception of whether their close friends would disapprove of their cannabis use (regardless of how much they use), rated as: 1 Not disapprove 2 Disapprove 3 Strongly disapprove

Time frame: 6 months post-baseline

Population: Number of participants analyzed is due to missing data

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionPeer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey1.1 score on the single itemStandard Deviation 0.4
ControlPeer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey1.1 score on the single itemStandard Deviation 0.3
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.81395% CI: [-0.398, 0.313]t-test, 2 sided
Secondary

Peer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey

One item rating of current perception of whether their close friends would disapprove of their cannabis use (regardless of how much they use), rated as: 1. Not disapprove 2. Disapprove 3. Strongly disapprove

Time frame: 3 months post-baseline

Population: Number of participants analyzed is due to missing data

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionPeer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey1.0 score on the single itemStandard Deviation 0.2
ControlPeer Approval/Disapproval of Cannabis Use as Measured by Item Modified From Monitoring the Future Survey1.0 score on the single itemStandard Deviation 0.1
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.49795% CI: [-0.728, 0.334]t-test, 2 sided
Secondary

Perceived Risk of Cannabis Use as Measured by 2 Modified Items From the Monitoring the Future Survey

Two items rating current opinion on a scale from no risk to great risk of their perceived risk harm from occasional cannabis use and regular use. Items are-- How much do you think people risk harming themselves (physically or in other ways), if they: 1. Use marijuana or marijuana products occasionally 2. Use marijuana or marijuana products regularly Response options are: 1. No risk 2. Slight risk 3. Moderate risk 4. Great risk Answers from both items are added together. The total range of two items summed can be 2-8. Higher totals indicate higher perceived risk.

Time frame: 3-months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionPerceived Risk of Cannabis Use as Measured by 2 Modified Items From the Monitoring the Future Survey3.1 total of two itemsStandard Deviation 1.1
ControlPerceived Risk of Cannabis Use as Measured by 2 Modified Items From the Monitoring the Future Survey3.5 total of two itemsStandard Deviation 1.1
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.42295% CI: [-0.21, 0.495]t-test, 2 sided
Secondary

Perceived Risk of Cannabis Use as Measured by Modified Items From the Monitoring the Future Survey

Two items rating current opinion on a scale from no risk to great risk of their perceived risk harm from occasional cannabis use and regular use. Items are-- How much do you think people risk harming themselves (physically or in other ways), if they: 1. Use marijuana or marijuana products occasionally 2. Use marijuana or marijuana products regularly Response options are: 1. No risk 2. Slight risk 3. Moderate risk 4. Great risk Answers from both items are added together. The total range of two items summed can be 2-8. Higher totals indicate higher perceived risk.

Time frame: 6-months post-baseline

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionPerceived Risk of Cannabis Use as Measured by Modified Items From the Monitoring the Future Survey3.3 total of two itemsStandard Deviation 1.2
ControlPerceived Risk of Cannabis Use as Measured by Modified Items From the Monitoring the Future Survey3.5 total of two itemsStandard Deviation 1.3
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIsp-value: 0.88295% CI: [-0.328, 0.381]t-test, 2 sided
Secondary

Quantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess the quantity of alcohol consumed.

Time frame: 3 months post-baseline

Population: Number of participants analyzed is due to focus on alcohol drinkers only

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionQuantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)17.1 estimated standard drinksStandard Deviation 28.1
ControlQuantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)12.4 estimated standard drinksStandard Deviation 15.4
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.20995% CI: [-0.686, 0.156]t-test, 2 sided
Secondary

Quantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)

30-day TLFB self-report will be used to assess the quantity of alcohol consumed.

Time frame: 6 months post-baseline

Population: Number of participants analyzed is due to focus on alcohol drinkers only

ArmMeasureValue (MEAN)Dispersion
Social Media InterventionQuantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)14.3 estimated standard drinksStandard Deviation 27.5
ControlQuantity of Alcohol Consumption as Reported on the Timeline Follow-Back (TLFB)13.5 estimated standard drinksStandard Deviation 15.8
Comparison: We fixed linear mixed effects models adjusted for baseline values, balancing factors (age, sex, recreational cannabis), and included a random intercept for group because this is an individually randomized group treatment trial. We tested for treatment effects with a two-sided test of the coefficient for the treatment/control indicator, and estimated Cohen's D (mean difference between the 2 groups at follow-up divided by the total variation not captured by the fixed effects) along with 95% CIs.p-value: 0.62395% CI: [-0.541, 0.328]t-test, 2 sided

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026