Fistula in Ano
Conditions
Brief summary
In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much. the aim of this study is to evaluate the effectiveness of PRP gel in treatment of perianal fistula.
Detailed description
Perianal fistula is a chronic condition that seriously affects the patients' quality of life. There are different treatment modalities used in treatment. Recently sphincter preserving methods are becoming more popular with low complication rates. Most of this methods aiming the closure of fistula tract by different pathways. Platelet rich plasma (PRP) is used in a wide range of conditions in medicine. The investigator's team showed the effective treatment of pilonidal disease by use of PRP gel. In the recent study, aim to evaluate the effectiveness of PRP gel in treatment of perianal fistula. Patients with perianal fistula will be evaluated for the study. After taking permission with informed consent; cases will be included in the study. Cases with inflammatory bowel disease, platelet function disorders or connective tissue disorders that may alter wound healing will be excluded from the study. After, PRP application to the fistula tract patients will be taken to follow up. Perianal fistulas will be followed by magnetic resonance imaging 1 month after the application. Pre-application and post-application scans will be used for the evaluation of the treatment success.
Interventions
OTHERplatelet rich plasma
platelet rich plasma prepared from the patients' own blood will be applied to the fistula tract
Sponsors
Uşak University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
PRP gel will be applicated to all cases
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients with perianal fistula * signing the informed consent form * above the age of 18
Exclusion criteria
* inflammatory bowel disease * previous radiation therapy * having connective tissue disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| percentage of the cure rate | 1 month | closure of the fistula tract will be evaluated by physical examination and magnetic resonance imaging |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORBarış Sevinç, M.D.
Uşak University Medical School
Outcome results
None listed