Occlusal Reduction Effect on Postendodontic Pain

Postendodontic Pain Following Occlusal Reduction in Mandibular Posterior Teeth: a Single-centre Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04186897

Enrollment

308

Registered

2019-12-05

Start date

2014-09-30

Completion date

2016-12-31

Last updated

2019-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic Irreversible Pulpitis

Brief summary

The aim of this study, thus, was to assess the effect of occlusal reduction on postendodontic pain after the first (post-instrumentation) and the second (post-obturation) visit in mandibular posterior teeth with symptomatic irreversible pulpitis and sensitivity to percussion treated in two visits.

Detailed description

The purpose of this randomized clinical trial was to evaluate the effect of occlusal reduction on post-instrumentation and post-obturation pain in mandibular posterior teeth with symptomatic irreversible pulpitis and sensitivity to percussion treated in two visits. Three hundred and eight patients were included in this study. Inclusion criteria were posterior mandibular teeth having symptomatic irreversible pulpitis with sensitivity to percussion. Patients were randomized into two equal groups. In the intervention group, occlusal reduction was done, while, in the control group, the occlusal surfaces were left intact. Conventional endodontic treatment was performed in two visits using a rotary nickel-titanium system followed by the lateral-condensation obturation technique. Post-instrumentation pain was assessed after 6, 12, 24 and 48 hours following the first visit, and post-obturation pain after 6 and 12 hours following the second visit. Each patient received a pain diary to record their pain levels and rescue medication intake.

Interventions

PROCEDUREOcclusal reduction

Occlusal contacts on the functional and non-functional cusps were reduced.

PROCEDURESham occlusal reduction

The occlusal surface left intact. No actual occlusal reduction.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Healthy adults 18-65 years old. * The diagnosis of symptomatic irreversible pulpitis with sensitivity to percussion. * Posterior mandibular teeth.

Exclusion criteria

* Pregnant women. * Patients who reported bruxism or clenching. * Patients who took analgesics during the last 12 hours before treatment start. * Teeth with no occlusal contact. * Unrestorable teeth.

Design outcomes

Primary

Measure	Time frame	Description
Post-instrumentation pain using a pain-measuring scale	6 hours	Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured.
Post-obturation pain using a pain-measuring scale	6 hours	Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured.

Secondary

Measure	Time frame	Description
Sham analgesic intake incidence	7 days	Sham medication intake incidence (Yes/No) taken as an initial rescue medication in case of postoperative pain.
Analgesic intake incidence	7 days	Analgesic intake incidence (Yes/No) as a rescue medication in case postoperative pain persisted after the sham analgesic intake.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026