Xerostomia
Conditions
Brief summary
The purpose of the clinical trial is to evaluate and validate the performance of the experimental mouth spray when used by persons with mild to severe dry mouth symptoms.
Detailed description
The purpose of this study is to investigate the efficacy of 3M Dry Mouth Moisturizing Spray to reduce symptoms of dry mouth for up to 4 hours and after 7 days of use. In addition, this study aims to support comparative claims.
Interventions
DEVICE3M Dry Mouth Moisturizing Spray to Biotene Moisturizing Mouth Spray
20 ml bottle
DEVICEBiotene Moisturizing Mouth Spray to 3M Dry Mouth Moisturizing Spray
44.3 ml bottle
Sponsors
3M
Solventum US LLC
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
All subjects completing the wash-in procedures and meeting inclusion/exclusion criteria will undergo a pre-study 5-hour visit (the day before randomization) to assess the effect of water on their dry mouth symptoms. The subjects will return the next day for confirmation that inclusion/exclusion criteria and the wash-in procedures continue to be met or followed. Eligible subjects will be randomized at this baseline visit in a 1:1 ratio to one of two treatment orders: A-\>B (AB) or B-\>A (BA).
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Screening - Start of Wash-In Visit * Subject who is ≥18 years of age and complains of dry mouth * Only 1 subject per household is allowed into study * Subject with a Challacombe scale score of 1 or higher * Subject agrees to refrain from eating spicy foods and foods containing garlic beginning 48-hours prior to all study visits * Subject agrees to eat a meal prior to all study visits that include sample evaluation in the clinic * Subject agrees to not eat, drink, chew tobacco, chew gum, smoke, brush or floss teeth for 2-hours prior to sample evaluation study visits * Subject agree to not use any oral care products and any type of breath mint or lozenges for 2-hours prior to sample evaluation study visits * Subject agrees to refrain from any food and liquid during the 5-hour study visits except for what is provided by the study research staff (e.g., water and treatments A and B during evaluation periods) * Subject agrees to only use those clinical oral care supplies provided during the entire study * Able to understand and willing to sign the Informed Consent Form Water Only Evaluation Visit * Subject has successfully completed a ≥ 2-day wash-in period * Subject has Challacombe scale score of 1 or higher * Subject has refrained from eating spicy foods and foods containing garlic beginning 48-hours prior to the sample evaluation visits * Subject ate a meal prior to sample evaluation study visits * Subject has not eaten, drank, chewed tobacco, chewed gum, smoked, brushed or flossed teeth for 2-hours prior to sample evaluation study visits * Subject has not used any oral care products, any type of breath mint or lozenges for 2-hours prior to sample evaluation study visits * Subject agrees to refrain from any food and liquid during the 5-hour study visits except for what is provided by the study research staff (e.g., water and treatments A and B during evaluation periods) * Subject has used only those clinical oral care supplies provided during study Baseline Period 1/Randomization Visit * Subject has successfully completed a ≥ 2-day wash-in period * Subject has a Challacombe Scale score of 1 or higher * Subject has refrained from eating spicy foods and foods containing garlic beginning 48-hours prior to sample evaluation study visits * Subject ate a meal prior to sample evaluation study visits * Subject has not eaten, drank, chewed tobacco, chewed gum, smoked, brushed or flossed teeth for 2-hours prior to sample evaluation study visits * Subject has not used any oral care products and any type of breath mint or lozenges for 2-hours prior to sample evaluation study visits * Subject agrees to refrain from any food and liquid during the 5-hour study visits except for what is provided by the study research staff (e.g., water and treatments A and B during evaluation periods) * Subject has used only those clinical oral care supplies provided during study
Exclusion criteria
Subject
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 10 cm Mouth Dryness Visual Analog Score | 15 minutes post dose | Primary endpoint will be paired-difference in Visual Analog Scale (VAS) between experimental and active control product. On the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 10 cm Mean Mouth Dryness Visual Analog Score | 240 minutes post dose | Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms |
| 10 cm Mouth Dryness Visual Analog Score | 240 minutes | Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water. |
| 10 cm Mean Mouth Dryness Visual Analog Scale | 30 minutes | Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms |
| 10 cm Mouth Dryness Visual Analog Scale | 5 minutes | Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water. |
| Response on Dry Mouth Relief | 5 minutes | Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent |
| Response to Effectively Lubricates the Mouth | 5 minutes | 5 point ordinal scale 1 = Poor and 5 = Excellent |
| Response to Feel Comfortable in the Mouth | 5 minutes | 5 point ordinal scale 1 = Poor and 5 = Excellent |
| Response to Soothing in the Mouth | 5 minutes | 5 point ordinal scale 1 = Poor and 5 = Excellent |
| Response to Effectively Moistens the Mouth | 5 minutes | 5 point ordinal scale 1 = Poor and 5 = Excellent |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| 3M Spray Then Biotene Spray 3M Dry Mouth Moisturizing Spray then Biotene Dry Mouth Moisturizing Spray | 20 |
| Biotene Spray Then 3M Spray Biotene Dry Mouth Moisturizing Spray then 3M Dry Mouth Moisturizing Spray | 20 |
| Total | 40 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 |
|---|---|---|---|
| Period 1: 7 Days | Adverse Event | 1 | 0 |
Baseline characteristics
| Characteristic | 3M Spray Then Biotene Spray | Biotene Spray Then 3M Spray | Total |
|---|---|---|---|
| Age, Continuous | 49.1 years STANDARD_DEVIATION 13.67 | 49.7 years STANDARD_DEVIATION 14.88 | 49.4 years STANDARD_DEVIATION 14.11 |
| Currently using Dry Mouth Products Currently using dry mouth products | 2 Participants | 2 Participants | 4 Participants |
| Currently using Dry Mouth Products Not currently using dry mouth products | 18 Participants | 18 Participants | 36 Participants |
| Ethnicity (NIH/OMB) Hispanic or Latino | 7 Participants | 11 Participants | 18 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 13 Participants | 9 Participants | 22 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants | 1 Participants | 1 Participants |
| Race (NIH/OMB) Asian | 2 Participants | 2 Participants | 4 Participants |
| Race (NIH/OMB) Black or African American | 1 Participants | 2 Participants | 3 Participants |
| Race (NIH/OMB) More than one race | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 1 Participants | 0 Participants | 1 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) White | 16 Participants | 15 Participants | 31 Participants |
| Region of Enrollment United States | 20 Participants | 20 Participants | 40 Participants |
| Sex: Female, Male Female | 13 Participants | 12 Participants | 25 Participants |
| Sex: Female, Male Male | 7 Participants | 8 Participants | 15 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 40 | 0 / 39 |
| other Total, other adverse events | 7 / 40 | 7 / 39 |
| serious Total, serious adverse events | 1 / 40 | 0 / 39 |
Outcome results
Primary
10 cm Mouth Dryness Visual Analog Score
Primary endpoint will be paired-difference in Visual Analog Scale (VAS) between experimental and active control product. On the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms.
Time frame: 15 minutes post dose
Population: Intent to treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Score | 4.51 cm | Standard Deviation 2.228 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Score | 4.6 cm | Standard Deviation 2.604 |
95% CI: [-1.2601, 0.5749]Mixed Models Analysis
Secondary
10 cm Mean Mouth Dryness Visual Analog Scale
Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms
Time frame: 60 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 4.58 cm | Standard Deviation 2.092 |
| Biotene Moisturizing Mouth Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 5.04 cm | Standard Deviation 2.168 |
Secondary
10 cm Mean Mouth Dryness Visual Analog Scale
Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms
Time frame: 120 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 4.86 cm | Standard Deviation 1.832 |
| Biotene Moisturizing Mouth Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 5.41 cm | Standard Deviation 2.143 |
Secondary
10 cm Mean Mouth Dryness Visual Analog Scale
Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms
Time frame: 30 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 4.51 cm | Standard Deviation 2.172 |
| Biotene Moisturizing Mouth Spray | 10 cm Mean Mouth Dryness Visual Analog Scale | 4.75 cm | Standard Deviation 2.403 |
Secondary
10 cm Mean Mouth Dryness Visual Analog Score
Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms
Time frame: 240 minutes post dose
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mean Mouth Dryness Visual Analog Score | 5.14 cm | Standard Deviation 1.689 |
| Biotene Moisturizing Mouth Spray | 10 cm Mean Mouth Dryness Visual Analog Score | 5.68 cm | Standard Deviation 2.261 |
Secondary
10 cm Mean Mouth Dryness Visual Analog Score
Mean Visual Analog Scale (VAS) on the scale 0 represents normal and 10 represents worst imaginable dry mouth symptoms
Time frame: 5 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mean Mouth Dryness Visual Analog Score | 4.54 cm | Standard Deviation 2.128 |
| Biotene Moisturizing Mouth Spray | 10 cm Mean Mouth Dryness Visual Analog Score | 4.62 cm | Standard Deviation 2.703 |
Secondary
10 cm Mouth Dryness Visual Analog Scale
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 5 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Scale | -2.203 cm | Standard Error 0.3042 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Scale | -1.871 cm | Standard Error 0.378 |
Secondary
10 cm Mouth Dryness Visual Analog Scale
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 30 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Scale | -2.420 cm | Standard Error 0.3111 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Scale | -1.900 cm | Standard Error 0.3176 |
Secondary
10 cm Mouth Dryness Visual Analog Scale
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 15 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Scale | -2.394 cm | Standard Error 0.3095 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Scale | -2.036 cm | Standard Error 0.3476 |
Secondary
10 cm Mouth Dryness Visual Analog Score
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 60 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Score | -2.455 cm | Standard Error 0.3172 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Score | -1.833 cm | Standard Error 0.309 |
Secondary
10 cm Mouth Dryness Visual Analog Score
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 240 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Score | -2.322 cm | Standard Error 0.3115 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Score | -1.665 cm | Standard Error 0.3576 |
Secondary
10 cm Mouth Dryness Visual Analog Score
Paired-difference Visual Analog Scale (VAS) between both experimental and active control against water control. The range of possible values is -10 to +10. A negative value means is a better outcome than water. A positive value means is a worse outcome than water.
Time frame: 120 minutes
Population: Intent to Treat (ITT) with Group Means Imputation
| Arm | Measure | Value (LEAST_SQUARES_MEAN) | Dispersion |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | 10 cm Mouth Dryness Visual Analog Score | -2.364 cm | Standard Error 0.3108 |
| Biotene Moisturizing Mouth Spray | 10 cm Mouth Dryness Visual Analog Score | -1.657 cm | Standard Error 0.3281 |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 120 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 15 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 14 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 5 Participants |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 5 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 4 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 16 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 6 Participants |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 15 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 16 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 10 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 19 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 30 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 17 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 21 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 8 Participants |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 60 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 18 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 22 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 7 Participants |
Secondary
Response on Dry Mouth Relief
Count of each category of the ordinal scale 0 = No Relief and 4 = Significant/Excellent
Time frame: 240 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 0=No Relief | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 3=Very Good | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 1=Not Enough | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 0 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response on Dry Mouth Relief | 2=Some/Good | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 4=Significant/Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 0=No Relief | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 2=Some/Good | 11 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 3=Very Good | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response on Dry Mouth Relief | 1=Not Enough | 16 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 60 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 13 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 7 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 5 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 16 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 4 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 15 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 15 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 10 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 17 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 3 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 30 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 15 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 8 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 120 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 15 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 5 Participants |
Secondary
Response to Effectively Lubricates the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 240 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 3= Good | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 1= Poor | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 2= Fair | 18 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 3= Good | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Lubricates the Mouth | 4= Very Good | 4 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 240 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 0 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 20 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 4 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 120 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 16 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 1 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 6 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 60 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 8 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 30 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 3 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 19 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 7 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 15 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 18 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 6 Participants |
Secondary
Response to Effectively Moistens the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 5 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 2= Fair | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 3= Good | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 5= Excellent | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 2= Fair | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 3= Good | 17 Participants |
| Biotene Moisturizing Mouth Spray | Response to Effectively Moistens the Mouth | 4= Very Good | 5 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 5 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 6 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 15 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 5 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 16 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 8 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 30 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 16 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 3 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 20 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 6 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 60 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 15 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 3 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 11 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 13 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 10 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 120 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 9 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 3 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 11 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 14 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 8 Participants |
Secondary
Response to Feel Comfortable in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 240 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 3= Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 3 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 5 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 5= Excellent | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 1= Poor | 6 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 2= Fair | 14 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 3= Good | 11 Participants |
| Biotene Moisturizing Mouth Spray | Response to Feel Comfortable in the Mouth | 4= Very Good | 5 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 240 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 16 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 4 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 120 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 4 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 11 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 13 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 6 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 60 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 3 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 7 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 30 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 14 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 4 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 2 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 12 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 15 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 8 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 15 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 7 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 13 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 8 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 8 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 17 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 6 Participants |
Secondary
Response to Soothing in the Mouth
5 point ordinal scale 1 = Poor and 5 = Excellent
Time frame: 5 minutes
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 2= Fair | 6 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 4= Very Good | 12 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 3= Good | 10 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 5= Excellent | 11 Participants |
| 3M(TM) Dry Mouth Moisturizing Spray | Response to Soothing in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 5= Excellent | 9 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 1= Poor | 1 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 2= Fair | 7 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 3= Good | 16 Participants |
| Biotene Moisturizing Mouth Spray | Response to Soothing in the Mouth | 4= Very Good | 6 Participants |