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Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section

Perfusion Index Predicts Post-spinal Hypotension in Obese Parturients for Cesarean Section-A Prospective Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04186091
Enrollment
50
Registered
2019-12-04
Start date
2017-04-01
Completion date
2018-07-30
Last updated
2019-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perfusion Index Predicts Post-spinal Hypotension

Brief summary

Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients. The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient.

Detailed description

Abstract Background Hypotension is a common adverse effect of spinal anesthesia during caesarean section especially in obese patients. The aim of this study is to find out the correlation between baseline PI and post spinal hypotension in obese parturient. Methods After approval of ethical committee and written informed consent, fifty Parturients aged between 18- 40 years, ASA I and II with term singleton pregnancies with BMI between 25 &40 admitted for cesarean section under spinal anesthesia were recruited in this prospective, observational study. The primary outcome is the correlation between baseline perfusion index and post spinal hypotension. The secondary outcome is the correlation between BMI and the incidence of hypotension after spinal anesthesia. Heart rate, blood pressure, perfusion index before and after spinal induction using Masimo device, level of sensory block, dose of ephedrine required to correct hypotension, dose of atropine required to correct bradycardia, incidence of nausea, vomiting and shivering were recorded.

Interventions

PROCEDUREcorrelation between baseline perfusion index and decrease in systolic blood pressure post spinal induction

correlation between baseline perfusion index and decrease in systolic blood pressure post spinal induction

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Fifty parturient * Aged between 18- 40, * ASA I and II * With term singleton pregnancies * With 25 ≥ BMI≤ 40 * Conducted for cesarean section under spinal anesthesia

Exclusion criteria

* Emergency cases, * Placenta previa, * Preeclampsia, * Cardiovascular and cerebrovascular diseases, * Patient with contraindication for regional anesthesia * Patient with peripheral vascular diseases as DVT.

Design outcomes

Primary

MeasureTime frameDescription
correlation between baseline perfusion index and post spinal decrease in systolic blood pressure24 hours Postoperativecorrelation between baseline perfusion index and post spinal decrease in systolic blood pressure

Secondary

MeasureTime frameDescription
correlation between BMI and the incidence of post-spinal hypotension24 hours Postoperativecorrelation between BMI and the incidence of post-spinal hypotension

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026