LAM, Lymphangioleiomyomatosis, Pulmonary Rehabilitation
Conditions
Brief summary
Data from patients with the orphan disease of lymphangioleiomyomatosis (LAM) which performed a pulmonary Rehabilitation program will be analyzed retrospectively. Data will be taken from the internal data base of the reference Center (Schoen Klinik Berchtesgadener Land, Schoenau, Germany) where These data were collected during clinical routine. Data will be included from the year 2000 until now. A retrospectively matched COPD cohort will be included for comparison.
Interventions
OTHERPulmonary Rehabilitation
Patients will perform a comprehensive, inpatient pulmonary rehabilitation program for 4 weeks duration
Sponsors
Schön Klinik Berchtesgadener Land
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* confirmed diagnosis of Lymphangioleiomyomatosis * performed a pulmonary Rehabilitation program at the reference center
Exclusion criteria
* missing data * repeated stay for pulmonary Rehabilitation at the reference center
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline 6 Minute walk distance at week 4 | baseline and week 4 | the walked distance in meter will be the Primary outcome of the 6 Minute walk test |
| Change from baseline Quality of life at week 4 | baseline and week 4 | the physical and mental health component summary score from the Short Form 36 Health Questionnaire will be recorded. Score range from 0 to 100 with lower scores indicating worse impairment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline lung function at week 4 | baseline and week 4 | forced expiratory volume in 1 second and inspiratory vital capacity will be provided in Liter and percent predicted |
Countries
Germany
Outcome results
None listed